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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM21A
All Species:
4.55
Human Site:
T72
Identified Species:
12.5
UniProt:
Q641Q2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q641Q2
NP_001005751.1
1341
147184
T72
V
D
G
L
I
R
E
T
K
A
T
D
C
R
L
Chimpanzee
Pan troglodytes
XP_001140122
1427
155633
T160
V
D
G
L
I
R
E
T
K
A
T
D
C
R
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534948
1205
132612
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGL7
1334
145292
K72
D
G
L
I
Q
E
T
K
A
T
H
C
R
L
H
Rat
Rattus norvegicus
Q80X08
1328
145131
K72
D
G
L
I
Q
E
T
K
A
T
H
C
R
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234527
1326
146323
C72
S
E
T
K
V
A
D
C
R
L
H
N
V
F
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001039320
401
44860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBW7
1469
160880
P103
K
K
K
K
P
E
L
P
L
K
S
S
E
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800027
2367
254413
A86
M
D
S
L
V
H
D
A
K
S
A
D
S
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
65.9
N.A.
73.5
72.7
N.A.
N.A.
55.4
N.A.
21.7
N.A.
20.4
N.A.
N.A.
24.1
Protein Similarity:
100
92.6
N.A.
70.6
N.A.
80.5
80
N.A.
N.A.
68.7
N.A.
26.2
N.A.
36.6
N.A.
N.A.
36.2
P-Site Identity:
100
100
N.A.
0
N.A.
0
0
N.A.
N.A.
0
N.A.
0
N.A.
6.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
33.3
N.A.
0
N.A.
13.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
12
23
23
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
23
23
0
0
% C
% Asp:
23
34
0
0
0
0
23
0
0
0
0
34
0
0
0
% D
% Glu:
0
12
0
0
0
34
23
0
0
0
0
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
23
23
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
34
0
0
0
23
% H
% Ile:
0
0
0
23
23
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
12
23
0
0
0
23
34
12
0
0
0
0
0
% K
% Leu:
0
0
23
34
0
0
12
0
12
12
0
0
0
23
34
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% N
% Pro:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
23
0
0
12
0
0
0
23
34
0
% R
% Ser:
12
0
12
0
0
0
0
0
0
12
12
12
12
0
0
% S
% Thr:
0
0
12
0
0
0
23
23
0
23
23
0
0
0
0
% T
% Val:
23
0
0
0
23
0
0
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _