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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METRNL All Species: 14.85
Human Site: S179 Identified Species: 40.83
UniProt: Q641Q3 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q641Q3 NP_001004431.1 311 34398 S179 L V R R H R A S D L H E L S A
Chimpanzee Pan troglodytes XP_001173613 387 42529 S255 L I R R P R A S D L H E L S A
Rhesus Macaque Macaca mulatta XP_001114398 339 37047 S207 L I R R H R A S D L H E L S A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VE43 311 34511 L179 L M S G Q R G L D L H V L S A
Rat Rattus norvegicus Q5RJL6 311 34450 L179 L M S G Q R G L D L H V L S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512630 240 26540 R121 A A F R Y E L R D D G H P R R
Chicken Gallus gallus XP_415598 286 31766 S155 L M S R G I A S D L H T V S A
Frog Xenopus laevis A1L2K1 286 32125 S156 L I S Q R T L S D L H T V S D
Zebra Danio Brachydanio rerio Q7ZV46 286 31691 A156 L V N H R P G A D P Q S L S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70 77.5 N.A. N.A. 78.1 78.7 N.A. 36.6 61.7 57.8 50.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72 79.6 N.A. N.A. 85.2 85.5 N.A. 48.8 75.8 73.9 67.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 93.3 N.A. N.A. 53.3 53.3 N.A. 13.3 60 40 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 N.A. N.A. 60 60 N.A. 20 73.3 60 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 0 0 45 12 0 0 0 0 0 0 78 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 100 12 0 0 0 0 12 % D
% Glu: 0 0 0 0 0 12 0 0 0 0 0 34 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 23 12 0 34 0 0 0 12 0 0 0 0 % G
% His: 0 0 0 12 23 0 0 0 0 0 78 12 0 0 0 % H
% Ile: 0 34 0 0 0 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 89 0 0 0 0 0 23 23 0 78 0 0 67 0 0 % L
% Met: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 12 0 0 0 12 0 0 12 0 0 % P
% Gln: 0 0 0 12 23 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 0 34 56 23 56 0 12 0 0 0 0 0 12 12 % R
% Ser: 0 0 45 0 0 0 0 56 0 0 0 12 0 89 0 % S
% Thr: 0 0 0 0 0 12 0 0 0 0 0 23 0 0 0 % T
% Val: 0 23 0 0 0 0 0 0 0 0 0 23 23 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _