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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METRNL
All Species:
25.45
Human Site:
Y170
Identified Species:
70
UniProt:
Q641Q3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q641Q3
NP_001004431.1
311
34398
Y170
R
R
T
T
G
F
Q
Y
E
L
V
R
R
H
R
Chimpanzee
Pan troglodytes
XP_001173613
387
42529
Y246
R
R
T
T
G
F
Q
Y
E
L
I
R
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001114398
339
37047
Y198
R
R
T
T
G
F
Q
Y
E
L
I
R
R
H
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE43
311
34511
Y170
R
R
T
T
G
F
Q
Y
E
L
M
S
G
Q
R
Rat
Rattus norvegicus
Q5RJL6
311
34450
Y170
R
R
T
T
G
F
Q
Y
E
L
M
S
G
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512630
240
26540
R112
P
H
R
D
I
S
R
R
V
A
A
F
R
Y
E
Chicken
Gallus gallus
XP_415598
286
31766
Y146
R
K
I
T
G
F
Q
Y
E
L
M
S
R
G
I
Frog
Xenopus laevis
A1L2K1
286
32125
Y147
R
K
I
T
G
F
Q
Y
E
L
I
S
Q
R
T
Zebra Danio
Brachydanio rerio
Q7ZV46
286
31691
Y147
R
K
I
T
A
F
Q
Y
E
L
V
N
H
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.5
N.A.
N.A.
78.1
78.7
N.A.
36.6
61.7
57.8
50.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72
79.6
N.A.
N.A.
85.2
85.5
N.A.
48.8
75.8
73.9
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
93.3
N.A.
N.A.
73.3
73.3
N.A.
6.6
60
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
N.A.
N.A.
80
80
N.A.
20
73.3
73.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
89
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
78
0
0
0
0
0
0
0
23
12
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
12
23
0
% H
% Ile:
0
0
34
0
12
0
0
0
0
0
34
0
0
0
12
% I
% Lys:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% P
% Gln:
0
0
0
0
0
0
89
0
0
0
0
0
12
23
0
% Q
% Arg:
89
56
12
0
0
0
12
12
0
0
0
34
56
23
56
% R
% Ser:
0
0
0
0
0
12
0
0
0
0
0
45
0
0
0
% S
% Thr:
0
0
56
89
0
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
12
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _