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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
5.45
Human Site:
S154
Identified Species:
10
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
S154
S
F
H
A
Q
S
E
S
E
T
V
G
K
N
G
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
S154
S
F
R
A
Q
S
E
S
E
T
V
G
K
N
G
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
Dog
Lupus familis
XP_547980
771
84217
Q378
P
E
P
S
F
C
V
Q
T
K
S
E
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
S154
S
T
A
G
N
A
S
S
S
Q
R
K
R
G
E
Rat
Rattus norvegicus
NP_001129366
533
58457
Q154
A
G
N
A
S
S
S
Q
R
K
R
G
E
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
R52
V
S
L
R
D
Q
T
R
P
G
R
G
V
N
H
Chicken
Gallus gallus
XP_426463
507
56489
A132
T
H
K
D
S
S
T
A
P
K
G
I
R
P
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
G126
R
V
Q
V
S
P
V
G
L
L
G
P
P
G
F
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
L25
C
Q
R
Q
E
Q
N
L
K
R
Q
G
Q
G
S
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
R33
P
E
Y
G
P
E
F
R
P
F
I
P
P
P
P
Maize
Zea mays
NP_001147634
445
48986
P70
A
A
L
P
L
A
S
P
S
S
G
R
Y
I
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
G82
P
V
P
V
P
V
P
G
R
Y
V
S
K
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
93.3
0
6.6
N.A.
13.3
20
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
93.3
0
13.3
N.A.
26.6
40
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
26.6
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
20
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
24
0
16
0
8
0
0
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
0
0
8
8
16
0
16
0
0
8
8
0
16
% E
% Phe:
0
16
0
0
8
0
8
0
0
8
0
0
0
0
8
% F
% Gly:
0
8
0
16
0
0
0
16
0
8
24
39
0
24
24
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
8
24
0
8
24
0
0
% K
% Leu:
0
0
16
0
8
0
0
8
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
8
0
0
0
0
0
0
24
0
% N
% Pro:
24
0
16
8
16
8
8
8
24
0
0
16
16
24
8
% P
% Gln:
0
8
8
8
16
16
0
16
0
8
8
0
8
0
0
% Q
% Arg:
8
0
16
8
0
0
0
16
16
8
24
8
16
8
0
% R
% Ser:
24
8
0
8
24
31
24
24
16
8
8
8
0
0
16
% S
% Thr:
8
8
0
0
0
0
16
0
8
16
0
0
8
0
0
% T
% Val:
8
16
0
16
0
8
16
0
0
0
24
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _