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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
5.45
Human Site:
S163
Identified Species:
10
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
S163
T
V
G
K
N
G
S
S
F
Q
K
K
K
C
E
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
S163
T
V
G
K
N
G
S
S
F
Q
K
K
K
C
E
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
Dog
Lupus familis
XP_547980
771
84217
H387
K
S
E
T
P
G
K
H
G
N
S
L
Q
K
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
C163
Q
R
K
R
G
E
D
C
V
L
P
Y
I
P
K
Rat
Rattus norvegicus
NP_001129366
533
58457
L163
K
R
G
E
A
C
V
L
P
Y
I
P
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
G61
G
R
G
V
N
H
A
G
S
S
A
D
S
G
V
Chicken
Gallus gallus
XP_426463
507
56489
P141
K
G
I
R
P
Y
I
P
K
R
L
R
Q
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
P135
L
G
P
P
G
F
F
P
Q
F
A
G
S
T
T
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
L34
R
Q
G
Q
G
S
G
L
T
P
Y
V
P
K
R
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
R42
F
I
P
P
P
P
K
R
F
K
P
E
T
P
S
Maize
Zea mays
NP_001147634
445
48986
R79
S
G
R
Y
I
S
K
R
E
R
A
L
L
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
S91
Y
V
S
K
R
E
R
S
L
L
A
S
L
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
100
0
6.6
N.A.
0
13.3
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
0
20
N.A.
13.3
20
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
0
31
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
0
0
16
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
8
0
16
0
0
8
0
0
8
0
8
16
% E
% Phe:
8
0
0
0
0
8
8
0
24
8
0
0
0
0
0
% F
% Gly:
8
24
39
0
24
24
8
8
8
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
8
0
0
0
8
0
8
0
0
% I
% Lys:
24
0
8
24
0
0
24
0
8
8
16
16
24
16
16
% K
% Leu:
8
0
0
0
0
0
0
16
8
16
8
16
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
24
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
16
16
24
8
0
16
8
8
16
8
8
16
0
% P
% Gln:
8
8
0
8
0
0
0
0
8
16
0
0
16
0
0
% Q
% Arg:
8
24
8
16
8
0
8
16
0
16
0
8
0
8
8
% R
% Ser:
8
8
8
0
0
16
16
24
8
8
8
8
16
8
16
% S
% Thr:
16
0
0
8
0
0
0
0
8
0
0
0
8
8
16
% T
% Val:
0
24
0
8
0
0
8
0
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
8
0
0
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _