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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
8.48
Human Site:
S20
Identified Species:
15.56
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
S20
V
A
Y
D
D
S
D
S
E
A
E
T
E
H
A
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
S20
V
A
Y
D
D
S
D
S
E
A
E
T
E
H
A
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
Dog
Lupus familis
XP_547980
771
84217
S244
V
A
Y
D
D
S
E
S
E
A
E
T
E
P
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
R20
E
T
E
A
D
P
A
R
S
G
D
A
A
G
Q
Rat
Rattus norvegicus
NP_001129366
533
58457
R20
E
S
E
A
D
P
A
R
S
G
D
A
A
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
Chicken
Gallus gallus
XP_426463
507
56489
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
Maize
Zea mays
NP_001147634
445
48986
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
100
0
80
N.A.
6.6
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
0
86.6
N.A.
13.3
20
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
0
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
16
0
0
16
0
0
24
0
16
16
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
39
0
16
0
0
0
16
0
0
0
0
% D
% Glu:
16
0
16
0
0
0
8
0
24
0
24
0
24
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
24
0
24
16
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
24
0
0
0
% T
% Val:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _