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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
5.15
Human Site:
S371
Identified Species:
9.44
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
S371
R
T
G
K
V
M
R
S
Y
K
A
T
I
Q
Q
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
S373
G
K
V
L
R
E
Y
S
I
Q
I
Q
Q
T
L
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
F99
G
K
E
P
Q
V
T
F
P
I
R
E
P
S
R
Dog
Lupus familis
XP_547980
771
84217
S598
R
T
G
K
V
V
R
S
Y
K
A
T
I
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
G362
R
T
G
K
V
V
K
G
Y
K
A
T
I
Q
Q
Rat
Rattus norvegicus
NP_001129366
533
58457
G360
R
T
G
K
V
V
K
G
Y
K
A
T
I
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
H256
C
P
V
L
Q
R
S
H
L
L
L
S
V
S
M
Chicken
Gallus gallus
XP_426463
507
56489
K336
C
K
V
T
R
V
Y
K
A
A
V
Q
Q
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
L330
V
W
D
F
K
T
G
L
C
V
K
C
I
P
A
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
G229
H
Q
Y
A
G
K
L
G
Q
I
L
A
V
E
F
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
I237
G
N
V
V
R
E
Y
I
R
G
L
G
P
I
L
Maize
Zea mays
NP_001147634
445
48986
Q274
G
L
V
T
K
E
F
Q
R
S
L
G
T
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
V286
N
K
F
V
H
E
Y
V
R
D
L
G
P
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
6.6
0
93.3
N.A.
80
80
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
13.3
13.3
100
N.A.
93.3
93.3
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
8
31
8
0
0
8
% A
% Cys:
16
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
31
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
8
8
0
0
8
8
0
0
0
0
0
0
8
% F
% Gly:
31
0
31
0
8
0
8
24
0
8
0
24
0
0
0
% G
% His:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
16
8
0
39
24
0
% I
% Lys:
0
31
0
31
16
8
16
8
0
31
8
0
0
0
0
% K
% Leu:
0
8
0
16
0
0
8
8
8
8
39
0
0
0
39
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
8
0
0
0
24
8
0
% P
% Gln:
0
8
0
0
16
0
0
8
8
8
0
16
16
31
31
% Q
% Arg:
31
0
0
0
24
8
16
0
24
0
8
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
8
24
0
8
0
8
0
16
0
% S
% Thr:
0
31
0
16
0
8
8
0
0
0
0
31
8
16
0
% T
% Val:
8
0
39
16
31
39
0
8
0
8
8
0
16
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
31
0
31
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _