KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
4.55
Human Site:
S40
Identified Species:
8.33
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
S40
T
G
Q
Q
K
D
T
S
G
V
A
R
P
P
G
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
S40
T
G
Q
Q
K
D
T
S
G
V
A
R
P
P
G
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
Dog
Lupus familis
XP_547980
771
84217
P264
A
S
Q
M
K
D
T
P
D
V
V
E
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
M40
G
M
S
R
P
S
G
M
G
F
A
S
S
T
V
Rat
Rattus norvegicus
NP_001129366
533
58457
E40
G
I
S
R
P
E
V
E
F
A
S
S
T
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
Chicken
Gallus gallus
XP_426463
507
56489
E18
S
E
P
E
A
E
T
E
K
A
D
D
L
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
K12
R
Q
E
T
I
S
P
K
N
V
P
F
Q
P
V
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
Maize
Zea mays
NP_001147634
445
48986
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
100
0
53.3
N.A.
13.3
0
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
0
53.3
N.A.
20
20
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
0
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
0
16
24
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
24
0
0
8
0
8
8
0
0
0
% D
% Glu:
0
8
8
8
0
16
0
16
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% F
% Gly:
16
16
0
0
0
0
8
0
24
0
0
0
0
16
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
24
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
16
0
8
8
0
0
8
0
24
31
0
% P
% Gln:
0
8
24
16
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
16
0
0
0
0
0
0
0
16
0
0
0
% R
% Ser:
8
8
16
0
0
16
0
16
0
0
8
16
8
0
0
% S
% Thr:
16
0
0
8
0
0
31
0
0
0
0
0
8
8
8
% T
% Val:
0
0
0
0
0
0
8
0
0
31
8
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _