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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
6.06
Human Site:
T177
Identified Species:
11.11
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
T177
E
D
C
V
V
P
Y
T
P
R
R
L
R
Q
R
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
T177
E
D
C
V
V
P
Y
T
P
R
R
L
R
Q
R
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
Dog
Lupus familis
XP_547980
771
84217
V401
K
R
C
E
D
C
I
V
P
Y
T
P
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
A177
K
R
L
R
Q
L
Q
A
L
N
P
E
A
G
G
Rat
Rattus norvegicus
NP_001129366
533
58457
N177
L
R
Q
L
Q
V
L
N
P
E
A
T
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
R75
V
E
G
E
A
R
P
R
S
G
R
S
G
W
Q
Chicken
Gallus gallus
XP_426463
507
56489
K155
N
T
S
T
C
E
R
K
E
S
D
Q
S
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
E149
T
S
Q
G
N
P
S
E
V
S
V
R
T
K
S
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
N48
R
L
R
K
S
N
D
N
S
S
D
D
H
Q
T
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
A56
S
Q
N
F
R
T
E
A
P
V
P
G
R
Y
I
Maize
Zea mays
NP_001147634
445
48986
S93
S
S
G
A
H
I
E
S
G
S
S
L
P
L
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
S105
T
I
P
T
P
D
Q
S
S
D
L
S
Q
K
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
100
0
13.3
N.A.
0
13.3
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
0
33.3
N.A.
6.6
20
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
16
0
0
8
0
8
0
0
% A
% Cys:
0
0
24
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
8
8
8
0
0
8
16
8
0
0
0
% D
% Glu:
16
8
0
16
0
8
16
8
8
8
0
8
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
8
0
0
0
0
8
8
0
8
16
16
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
8
% I
% Lys:
16
0
0
8
0
0
0
8
0
0
0
0
8
16
0
% K
% Leu:
8
8
8
8
0
8
8
0
8
0
8
24
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
8
0
16
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
24
8
0
39
0
16
8
8
0
8
% P
% Gln:
0
8
16
0
16
0
16
0
0
0
0
8
8
24
8
% Q
% Arg:
8
24
8
8
8
8
8
8
0
16
24
8
24
8
24
% R
% Ser:
16
16
8
0
8
0
8
16
24
31
8
16
8
0
16
% S
% Thr:
16
8
0
16
0
8
0
16
0
0
8
8
8
0
16
% T
% Val:
8
0
0
16
16
8
0
8
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _