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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR25
All Species:
17.58
Human Site:
T337
Identified Species:
32.22
UniProt:
Q64LD2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q64LD2
NP_001154948.1
544
60161
T337
G
R
S
D
F
R
I
T
T
L
K
F
H
P
K
Chimpanzee
Pan troglodytes
XP_001159477
546
60551
T337
G
R
S
D
F
R
I
T
T
L
K
F
H
P
K
Rhesus Macaque
Macaca mulatta
XP_001109245
270
29667
G67
G
S
C
E
D
P
G
G
H
R
L
P
L
A
Q
Dog
Lupus familis
XP_547980
771
84217
T564
A
Q
S
D
F
R
I
T
T
L
K
F
H
P
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_808270
535
58462
T328
G
Q
S
D
F
R
V
T
T
L
K
F
H
P
K
Rat
Rattus norvegicus
NP_001129366
533
58457
T326
G
H
S
D
F
R
V
T
T
L
K
F
H
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513053
427
46077
R224
P
Y
L
E
A
K
S
R
H
T
E
I
P
K
R
Chicken
Gallus gallus
XP_426463
507
56489
F304
F
R
I
S
T
L
K
F
H
P
T
D
S
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23256
501
54455
N298
R
T
M
R
G
H
T
N
Y
V
F
C
C
S
F
Sea Urchin
Strong. purpuratus
XP_788503
400
44994
D197
C
I
K
W
H
P
T
D
P
Q
M
F
I
S
G
Poplar Tree
Populus trichocarpa
XP_002319259
408
45567
F205
Q
V
V
G
V
I
K
F
C
P
D
N
S
N
I
Maize
Zea mays
NP_001147634
445
48986
F242
Q
A
V
E
V
I
K
F
N
P
S
N
P
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200263
457
50597
F254
E
V
V
G
V
V
K
F
H
P
D
N
C
N
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
45.2
54.3
N.A.
77.7
76.8
N.A.
27
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
31.4
Protein Similarity:
100
95.4
47
62
N.A.
84.9
84.5
N.A.
39.3
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.1
46.3
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
100
93.3
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Percent
Protein Identity:
30.5
29.7
N.A.
29
N.A.
N.A.
Protein Similarity:
46.8
45.7
N.A.
47.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
6.6
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
8
0
8
0
0
0
0
0
8
0
0
8
16
0
0
% C
% Asp:
0
0
0
39
8
0
0
8
0
0
16
8
0
8
0
% D
% Glu:
8
0
0
24
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
39
0
0
31
0
0
8
47
0
0
8
% F
% Gly:
39
0
0
16
8
0
8
8
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
8
8
0
0
31
0
0
0
39
0
0
% H
% Ile:
0
8
8
0
0
16
24
0
0
0
0
8
8
0
8
% I
% Lys:
0
0
8
0
0
8
31
0
0
0
39
0
0
8
39
% K
% Leu:
0
0
8
0
0
8
0
0
0
39
8
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
24
0
24
0
% N
% Pro:
8
0
0
0
0
16
0
0
8
31
0
8
16
39
0
% P
% Gln:
16
16
0
0
0
0
0
0
0
8
0
0
0
0
8
% Q
% Arg:
8
24
0
8
0
39
0
8
0
8
0
0
0
0
8
% R
% Ser:
0
8
39
8
0
0
8
0
0
0
8
0
16
16
0
% S
% Thr:
0
8
0
0
8
0
16
39
39
8
8
0
0
0
0
% T
% Val:
0
16
24
0
24
8
16
0
0
8
0
0
0
0
16
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _