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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEP135 All Species: 16.67
Human Site: S599 Identified Species: 30.56
UniProt: Q66GS9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q66GS9 NP_079285.2 1140 133504 S599 L E H I E E V S L F G K S E L
Chimpanzee Pan troglodytes XP_517281 1140 133474 S599 L E H I E E V S L F G K S E L
Rhesus Macaque Macaca mulatta XP_001084949 1131 132474 S599 L E H I E E M S L F G K S E L
Dog Lupus familis XP_539276 919 107911 A435 A Q K L S H V A G D S S H Q K
Cat Felis silvestris
Mouse Mus musculus Q6P5D4 1140 133327 N599 L K N I Q E R N A V G K S D L
Rat Rattus norvegicus Q9Z220 712 82993 L228 K K K Y E L Q L T Q E K I M C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518640 1143 132891 T601 L K N Q Q D L T I L G K S E L
Chicken Gallus gallus O42184 1433 161009 E791 S E Q L Q A A E K Q I Q N L E
Frog Xenopus laevis P85120 2058 236320 S759 K S E R L E V S Y Q G L N D E
Zebra Danio Brachydanio rerio Q5RG45 1164 134937 A604 L K V A H S T A L T D R E Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648749 1059 123068 L560 L R L R N E E L N D R L R Q M
Honey Bee Apis mellifera XP_001121524 648 75877 I164 F P L R R P V I E S E P L P K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781904 1062 122717 S573 R I T T E R D S L R E R L K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 93.5 71.8 N.A. 82.8 21.6 N.A. 69 20.2 20.9 51.6 N.A. 21.9 24.4 N.A. 28.1
Protein Similarity: 100 100 95.7 77.1 N.A. 92.8 40 N.A. 85 40.2 36.3 73.9 N.A. 45.1 38.5 N.A. 52.6
P-Site Identity: 100 100 93.3 6.6 N.A. 46.6 13.3 N.A. 40 6.6 26.6 13.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 100 100 33.3 N.A. 80 20 N.A. 86.6 33.3 40 40 N.A. 26.6 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 8 8 16 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 8 0 0 16 8 0 0 16 0 % D
% Glu: 0 31 8 0 39 47 8 8 8 0 24 0 8 31 24 % E
% Phe: 8 0 0 0 0 0 0 0 0 24 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 47 0 0 0 0 % G
% His: 0 0 24 0 8 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 31 0 0 0 8 8 0 8 0 8 0 0 % I
% Lys: 16 31 16 0 0 0 0 0 8 0 0 47 0 8 16 % K
% Leu: 54 0 16 16 8 8 8 16 39 8 0 16 16 8 39 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % M
% Asn: 0 0 16 0 8 0 0 8 8 0 0 0 16 0 0 % N
% Pro: 0 8 0 0 0 8 0 0 0 0 0 8 0 8 0 % P
% Gln: 0 8 8 8 24 0 8 0 0 24 0 8 0 24 0 % Q
% Arg: 8 8 0 24 8 8 8 0 0 8 8 16 8 0 0 % R
% Ser: 8 8 0 0 8 8 0 39 0 8 8 8 39 0 0 % S
% Thr: 0 0 8 8 0 0 8 8 8 8 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 39 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _