KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CEP135
All Species:
19.7
Human Site:
Y185
Identified Species:
36.11
UniProt:
Q66GS9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q66GS9
NP_079285.2
1140
133504
Y185
P
P
S
E
V
S
S
Y
P
V
P
Q
P
D
D
Chimpanzee
Pan troglodytes
XP_517281
1140
133474
Y185
P
P
S
E
V
S
S
Y
P
V
P
Q
P
D
D
Rhesus Macaque
Macaca mulatta
XP_001084949
1131
132474
Y185
P
P
S
E
V
S
S
Y
P
V
P
Q
P
D
D
Dog
Lupus familis
XP_539276
919
107911
T76
H
I
Q
E
L
M
E
T
K
E
T
V
T
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D4
1140
133327
Y185
P
P
S
E
V
S
A
Y
P
V
P
Q
P
E
D
Rat
Rattus norvegicus
Q9Z220
712
82993
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518640
1143
132891
Y185
P
P
S
G
L
S
A
Y
P
I
P
Q
P
S
D
Chicken
Gallus gallus
O42184
1433
161009
Y265
G
A
V
A
G
T
R
Y
F
Q
C
Q
P
R
Y
Frog
Xenopus laevis
P85120
2058
236320
H282
E
L
L
L
D
T
K
H
E
V
E
R
L
N
L
Zebra Danio
Brachydanio rerio
Q5RG45
1164
134937
P188
S
S
G
G
Y
V
P
P
A
V
A
Q
P
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648749
1059
123068
K189
C
N
A
G
V
F
Q
K
T
T
T
T
T
K
D
Honey Bee
Apis mellifera
XP_001121524
648
75877
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781904
1062
122717
K189
R
E
L
D
R
E
L
K
D
T
R
L
A
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.5
71.8
N.A.
82.8
21.6
N.A.
69
20.2
20.9
51.6
N.A.
21.9
24.4
N.A.
28.1
Protein Similarity:
100
100
95.7
77.1
N.A.
92.8
40
N.A.
85
40.2
36.3
73.9
N.A.
45.1
38.5
N.A.
52.6
P-Site Identity:
100
100
100
6.6
N.A.
86.6
0
N.A.
66.6
20
6.6
33.3
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
0
N.A.
86.6
26.6
33.3
33.3
N.A.
20
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
16
0
8
0
8
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
8
0
0
0
0
31
54
% D
% Glu:
8
8
0
39
0
8
8
0
8
8
8
0
0
8
16
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
8
24
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
16
8
0
0
0
0
8
0
% K
% Leu:
0
8
16
8
16
0
8
0
0
0
0
8
8
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
39
39
0
0
0
0
8
8
39
0
39
0
54
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
8
0
54
0
0
0
% Q
% Arg:
8
0
0
0
8
0
8
0
0
0
8
8
0
16
0
% R
% Ser:
8
8
39
0
0
39
24
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
16
0
8
8
16
16
8
16
8
0
% T
% Val:
0
0
8
0
39
8
0
0
0
47
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
47
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _