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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CEP135
All Species:
23.94
Human Site:
Y457
Identified Species:
43.89
UniProt:
Q66GS9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q66GS9
NP_079285.2
1140
133504
Y457
I
E
E
E
R
D
Y
Y
K
K
E
L
E
R
L
Chimpanzee
Pan troglodytes
XP_517281
1140
133474
Y457
I
E
E
E
R
D
Y
Y
K
K
E
L
E
R
L
Rhesus Macaque
Macaca mulatta
XP_001084949
1131
132474
Y457
I
E
E
E
R
D
Y
Y
K
K
E
L
E
R
L
Dog
Lupus familis
XP_539276
919
107911
Q302
E
K
H
M
E
D
I
Q
S
N
V
K
L
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D4
1140
133327
Y457
I
E
E
E
R
D
Y
Y
K
K
E
L
E
K
L
Rat
Rattus norvegicus
Q9Z220
712
82993
H95
S
P
K
S
T
T
A
H
A
I
L
R
R
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518640
1143
132891
Y461
L
E
E
D
R
D
H
Y
K
M
E
L
E
H
L
Chicken
Gallus gallus
O42184
1433
161009
E645
G
V
G
A
Q
T
A
E
F
A
E
L
K
T
Q
Frog
Xenopus laevis
P85120
2058
236320
F619
K
K
Q
L
Q
K
A
F
D
Q
S
K
E
Q
V
Zebra Danio
Brachydanio rerio
Q5RG45
1164
134937
Y464
L
E
E
E
R
N
Y
Y
R
E
E
V
E
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648749
1059
123068
S425
E
E
K
I
R
L
S
S
E
R
D
F
F
Q
K
Honey Bee
Apis mellifera
XP_001121524
648
75877
K31
D
A
L
P
L
I
E
K
L
L
A
D
L
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781904
1062
122717
K436
I
R
V
L
E
D
E
K
S
F
Y
K
R
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.5
71.8
N.A.
82.8
21.6
N.A.
69
20.2
20.9
51.6
N.A.
21.9
24.4
N.A.
28.1
Protein Similarity:
100
100
95.7
77.1
N.A.
92.8
40
N.A.
85
40.2
36.3
73.9
N.A.
45.1
38.5
N.A.
52.6
P-Site Identity:
100
100
100
6.6
N.A.
93.3
0
N.A.
66.6
13.3
6.6
60
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
100
13.3
N.A.
86.6
26.6
53.3
93.3
N.A.
46.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
24
0
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
54
0
0
8
0
8
8
0
0
0
% D
% Glu:
16
54
47
39
16
0
16
8
8
8
54
0
54
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
8
8
0
8
8
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
8
8
0
0
0
0
0
8
0
% H
% Ile:
39
0
0
8
0
8
8
0
0
8
0
0
0
8
0
% I
% Lys:
8
16
16
0
0
8
0
16
39
31
0
24
8
8
8
% K
% Leu:
16
0
8
16
8
8
0
0
8
8
8
47
16
8
39
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
16
0
0
8
0
8
0
0
0
16
16
% Q
% Arg:
0
8
0
0
54
0
0
0
8
8
0
8
16
31
0
% R
% Ser:
8
0
0
8
0
0
8
8
16
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
16
0
0
0
0
0
0
0
8
8
% T
% Val:
0
8
8
0
0
0
0
0
0
0
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
39
47
0
0
8
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _