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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM198 All Species: 17.58
Human Site: Y344 Identified Species: 35.15
UniProt: Q66K66 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q66K66 NP_001005209.1 360 39475 Y344 P T D A D Y E Y G S R G P L T
Chimpanzee Pan troglodytes XP_001163990 360 39440 Y344 P T D A D Y E Y G S R G P L T
Rhesus Macaque Macaca mulatta XP_001105408 360 39454 Y344 P T D A D Y E Y G S R G P L T
Dog Lupus familis XP_853325 242 26012 L227 P A A L W P L L N L M S V V V
Cat Felis silvestris
Mouse Mus musculus Q8BG75 360 39734 Y344 P T D T D Y E Y G S R G P L T
Rat Rattus norvegicus XP_002727282 360 39733 Y344 P T D T D Y E Y G S R G P L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512774 159 16398 P144 S R S D C W T P F P G H I D S
Chicken Gallus gallus XP_001232637 280 30956 V265 P L L T V L G V L V Q W K V T
Frog Xenopus laevis NP_001087727 342 38153 D322 T N M Q T I V D M D Y E C G S
Zebra Danio Brachydanio rerio Q498W5 369 40838 V347 M P S G H T S V D M D Y D C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608351 381 41714 N351 K S S S N E R N T F R S D R T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781273 312 35035 R285 E L Q K L R Q R E A R E E V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 65.2 N.A. 97.7 97.5 N.A. 26.1 27.2 50.5 59.8 N.A. 23.8 N.A. N.A. 33.8
Protein Similarity: 100 99.7 99.7 65.8 N.A. 98.3 98.3 N.A. 30 40.2 69.4 72.3 N.A. 44.8 N.A. N.A. 51.9
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 0 13.3 0 0 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 93.3 N.A. 13.3 26.6 6.6 0 N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 25 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 9 9 0 % C
% Asp: 0 0 42 9 42 0 0 9 9 9 9 0 17 9 0 % D
% Glu: 9 0 0 0 0 9 42 0 9 0 0 17 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 9 0 42 0 9 42 0 9 9 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % I
% Lys: 9 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 17 9 9 9 9 9 9 9 9 0 0 0 42 0 % L
% Met: 9 0 9 0 0 0 0 0 9 9 9 0 0 0 0 % M
% Asn: 0 9 0 0 9 0 0 9 9 0 0 0 0 0 0 % N
% Pro: 59 9 0 0 0 9 0 9 0 9 0 0 42 0 0 % P
% Gln: 0 0 9 9 0 0 9 0 0 0 9 0 0 0 0 % Q
% Arg: 0 9 0 0 0 9 9 9 0 0 59 0 0 9 9 % R
% Ser: 9 9 25 9 0 0 9 0 0 42 0 17 0 0 17 % S
% Thr: 9 42 0 25 9 9 9 0 9 0 0 0 0 0 59 % T
% Val: 0 0 0 0 9 0 9 17 0 9 0 0 9 25 9 % V
% Trp: 0 0 0 0 9 9 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 42 0 42 0 0 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _