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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPZ
All Species:
14.85
Human Site:
T181
Identified Species:
46.67
UniProt:
Q66K79
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q66K79
NP_001014447.1
652
73655
T181
L
P
S
G
L
P
P
T
F
I
R
F
S
H
H
Chimpanzee
Pan troglodytes
A5A6K7
476
53027
Y53
E
D
G
I
S
F
E
Y
H
R
Y
P
E
L
R
Rhesus Macaque
Macaca mulatta
XP_001097378
620
69212
D192
R
R
R
L
Q
Q
E
D
G
I
S
F
E
Y
H
Dog
Lupus familis
XP_545910
701
78267
E126
C
E
V
G
L
D
A
E
E
A
L
P
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4V4
654
73676
T186
L
A
S
G
L
P
P
T
F
I
R
F
A
H
H
Rat
Rattus norvegicus
O54858
652
73063
T184
L
P
S
G
L
P
P
T
F
I
R
F
A
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8QGP3
647
73900
T178
L
P
S
D
F
P
A
T
F
I
Q
F
K
H
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685713
653
74485
T184
I
S
D
G
G
L
S
T
V
I
Q
F
T
Y
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.6
36
70.6
N.A.
81
82.6
N.A.
N.A.
65.4
N.A.
56.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.6
50.1
74.8
N.A.
88.3
89.4
N.A.
N.A.
79.1
N.A.
73.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
20
20
N.A.
86.6
93.3
N.A.
N.A.
66.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
26.6
20
N.A.
93.3
100
N.A.
N.A.
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
25
0
0
13
0
0
25
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
13
13
0
13
0
13
0
0
0
0
0
0
0
% D
% Glu:
13
13
0
0
0
0
25
13
13
0
0
0
25
0
0
% E
% Phe:
0
0
0
0
13
13
0
0
50
0
0
75
0
0
0
% F
% Gly:
0
0
13
63
13
0
0
0
13
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
0
50
75
% H
% Ile:
13
0
0
13
0
0
0
0
0
75
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
50
0
0
13
50
13
0
0
0
0
13
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
38
0
0
0
50
38
0
0
0
0
25
0
0
0
% P
% Gln:
0
0
0
0
13
13
0
0
0
0
25
0
0
0
0
% Q
% Arg:
13
13
13
0
0
0
0
0
0
13
38
0
0
0
25
% R
% Ser:
0
13
50
0
13
0
13
0
0
0
13
0
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
63
0
0
0
0
13
0
0
% T
% Val:
0
0
13
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
13
0
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _