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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPZ All Species: 12.42
Human Site: Y332 Identified Species: 39.05
UniProt: Q66K79 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q66K79 NP_001014447.1 652 73655 Y332 F P D L T S E Y Y R L A E T R
Chimpanzee Pan troglodytes A5A6K7 476 53027 I185 G R S N A Q G I D L N R N F P
Rhesus Macaque Macaca mulatta XP_001097378 620 69212 A327 W F V G R S N A Q G I D L N R
Dog Lupus familis XP_545910 701 78267 Y258 Y E V A A A E Y Y R L A F S R
Cat Felis silvestris
Mouse Mus musculus Q8R4V4 654 73676 Y337 F P D L T S E Y Y R L A S T R
Rat Rattus norvegicus O54858 652 73063 Y335 F P D L T S E Y Y R L A S T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8QGP3 647 73900 A329 F P D L T S E A Y R R A G I R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685713 653 74485 Y336 P D L T S I F Y N R R R F R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.6 36 70.6 N.A. 81 82.6 N.A. N.A. 65.4 N.A. 56.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 49.6 50.1 74.8 N.A. 88.3 89.4 N.A. N.A. 79.1 N.A. 73.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 13.3 46.6 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 26.6 66.6 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 25 13 0 25 0 0 0 63 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 50 0 0 0 0 0 13 0 0 13 0 0 0 % D
% Glu: 0 13 0 0 0 0 63 0 0 0 0 0 13 0 0 % E
% Phe: 50 13 0 0 0 0 13 0 0 0 0 0 25 13 0 % F
% Gly: 13 0 0 13 0 0 13 0 0 13 0 0 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % H
% Ile: 0 0 0 0 0 13 0 13 0 0 13 0 0 13 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 13 50 0 0 0 0 0 13 50 0 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 13 0 13 0 13 0 13 13 0 % N
% Pro: 13 50 0 0 0 0 0 0 0 0 0 0 0 0 13 % P
% Gln: 0 0 0 0 0 13 0 0 13 0 0 0 0 0 0 % Q
% Arg: 0 13 0 0 13 0 0 0 0 75 25 25 0 13 75 % R
% Ser: 0 0 13 0 13 63 0 0 0 0 0 0 25 13 0 % S
% Thr: 0 0 0 13 50 0 0 0 0 0 0 0 0 38 0 % T
% Val: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 0 0 0 0 63 63 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _