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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E4F1
All Species:
4.55
Human Site:
S135
Identified Species:
16.67
UniProt:
Q66K89
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q66K89
NP_004415.2
784
83477
S135
A
A
D
I
S
H
A
S
D
L
V
G
G
G
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084651
784
83580
P135
A
A
D
I
S
H
A
P
D
L
V
G
G
G
H
Dog
Lupus familis
XP_862028
930
107454
Q225
I
S
T
L
T
L
H
Q
R
I
H
T
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCE9
783
84277
P136
A
E
D
I
S
H
A
P
D
L
V
G
S
G
H
Rat
Rattus norvegicus
XP_002724701
783
84261
P136
A
E
D
M
S
H
A
P
D
L
V
G
S
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414860
781
85768
S122
A
E
E
I
S
N
A
S
A
I
V
G
S
G
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4V8R6
719
80117
S106
K
Q
D
A
K
V
A
S
G
D
K
K
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
21.8
N.A.
88.3
87.6
N.A.
N.A.
67.9
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.5
37.8
N.A.
91.7
91
N.A.
N.A.
78.1
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
6.6
N.A.
80
73.3
N.A.
N.A.
60
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
33.3
N.A.
80
80
N.A.
N.A.
80
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
29
0
15
0
0
86
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
72
0
0
0
0
0
58
15
0
0
0
0
0
% D
% Glu:
0
43
15
0
0
0
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
72
43
72
0
% G
% His:
0
0
0
0
0
58
15
0
0
0
15
0
0
0
72
% H
% Ile:
15
0
0
58
0
0
0
0
0
29
0
0
0
0
0
% I
% Lys:
15
0
0
0
15
0
0
0
0
0
15
15
0
0
15
% K
% Leu:
0
0
0
15
0
15
0
0
0
58
0
0
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
0
0
0
15
0
15
% R
% Ser:
0
15
0
0
72
0
0
43
0
0
0
0
43
15
0
% S
% Thr:
0
0
15
0
15
0
0
0
0
0
0
15
0
0
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
72
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _