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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
26.67
Human Site:
S261
Identified Species:
48.89
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
S261
T
S
P
V
R
A
I
S
R
A
A
T
K
R
L
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
S261
T
S
P
V
R
A
I
S
R
A
A
T
K
R
L
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
S261
T
S
P
V
R
A
I
S
R
A
A
T
K
R
L
Dog
Lupus familis
XP_850664
607
68310
S261
T
S
P
V
R
A
I
S
R
A
A
T
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
S261
T
S
P
V
R
A
V
S
R
A
A
T
K
R
L
Rat
Rattus norvegicus
NP_001102279
607
67944
S261
T
S
P
V
R
A
I
S
R
A
A
T
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
G261
T
S
P
A
R
A
S
G
R
T
T
T
K
R
L
Chicken
Gallus gallus
XP_422568
607
67856
S261
T
S
P
V
R
A
V
S
R
T
P
S
K
R
L
Frog
Xenopus laevis
Q5FWQ6
415
45899
R80
K
I
G
Q
Q
D
S
R
Q
F
Y
L
F
K
V
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
G233
S
N
A
A
S
S
P
G
A
A
S
L
Q
R
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
R235
E
V
A
L
E
E
K
R
R
N
S
R
I
Q
D
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
K229
E
V
L
N
D
K
M
K
K
A
L
E
E
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
66.6
73.3
0
0
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
66.6
86.6
26.6
0
N.A.
46.6
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
0
62
0
0
8
62
47
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
16
0
0
0
8
8
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
39
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
8
8
8
8
0
0
0
62
8
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
8
16
0
0
62
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
62
0
0
0
8
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
8
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
62
0
0
16
70
0
0
8
0
70
0
% R
% Ser:
8
62
0
0
8
8
16
54
0
0
16
8
0
0
0
% S
% Thr:
62
0
0
0
0
0
0
0
0
16
8
54
0
0
0
% T
% Val:
0
16
0
54
0
0
16
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _