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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG16L1 All Species: 26.36
Human Site: S304 Identified Species: 48.33
UniProt: Q676U5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q676U5 NP_060444.3 607 68265 S304 N V D T H P G S G K E V R V P
Chimpanzee Pan troglodytes XP_001150112 607 68277 S304 N V D T H P G S G K E V R V P
Rhesus Macaque Macaca mulatta XP_001114814 607 68295 S304 N V D T H P G S G K E V R V P
Dog Lupus familis XP_850664 607 68310 S304 N V D T H P G S S K E V R V P
Cat Felis silvestris
Mouse Mus musculus Q8C0J2 607 68153 S304 I M D T H P A S G K D V R V P
Rat Rattus norvegicus NP_001102279 607 67944 S304 V V D T H P A S G K D V R V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520939 607 68368 S304 T M G A R S G S R K E V R V P
Chicken Gallus gallus XP_422568 607 67856 A304 N A E P H P G A S K E V R V P
Frog Xenopus laevis Q5FWQ6 415 45899 S123 C K V W D T A S G E E L H T L
Zebra Danio Brachydanio rerio NP_001017854 330 38008 R38 E I I H Q Y N R L L E K S D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733313 604 67257 I276 G L D D N E Y I S A R F T A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19124 578 65468 D278 N G D L L L G D S V P S R A E
Sea Urchin Strong. purpuratus XP_781454 582 65038 S272 S T L S R A P S L P P P V S F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.8 95.3 N.A. 94 93.9 N.A. 84.3 86.3 22.8 37.4 N.A. 38.3 N.A. 28.1 39
Protein Similarity: 100 99.8 99.6 97.8 N.A. 97 97 N.A. 91 93.9 37 45.6 N.A. 60.9 N.A. 47.1 57.8
P-Site Identity: 100 100 100 93.3 N.A. 73.3 80 N.A. 53.3 66.6 20 6.6 N.A. 6.6 N.A. 26.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 60 80 33.3 13.3 N.A. 20 N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 8 24 8 0 8 0 0 0 16 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 62 8 8 0 0 8 0 0 16 0 0 8 0 % D
% Glu: 8 0 8 0 0 8 0 0 0 8 62 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % F
% Gly: 8 8 8 0 0 0 54 0 47 0 0 0 0 0 8 % G
% His: 0 0 0 8 54 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 8 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 62 0 8 0 0 0 % K
% Leu: 0 8 8 8 8 8 0 0 16 8 0 8 0 0 16 % L
% Met: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 47 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 54 8 0 0 8 16 8 0 0 62 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 16 0 0 8 8 0 8 0 70 0 0 % R
% Ser: 8 0 0 8 0 8 0 70 31 0 0 8 8 8 0 % S
% Thr: 8 8 0 47 0 8 0 0 0 0 0 0 8 8 0 % T
% Val: 8 39 8 0 0 0 0 0 0 8 0 62 8 62 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _