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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
37.88
Human Site:
S425
Identified Species:
69.44
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Dog
Lupus familis
XP_850664
607
68310
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Rat
Rattus norvegicus
NP_001102279
607
67944
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
S425
L
G
K
S
L
I
V
S
G
S
H
D
R
T
L
Chicken
Gallus gallus
XP_422568
607
67856
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Frog
Xenopus laevis
Q5FWQ6
415
45899
L234
F
N
T
T
G
D
R
L
I
T
G
S
F
D
H
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
L149
C
R
E
L
R
N
C
L
A
D
L
E
R
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
T421
Q
E
P
I
K
V
V
T
G
S
H
D
R
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
G395
Q
S
H
S
A
V
S
G
S
A
D
R
V
I
K
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
S398
S
D
P
N
K
F
V
S
G
S
H
D
R
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
73.3
100
0
13.3
N.A.
53.3
N.A.
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
100
13.3
20
N.A.
80
N.A.
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
54
8
0
0
0
8
8
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
62
0
0
0
8
0
0
0
8
8
77
0
8
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
8
0
0
8
77
0
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
77
0
0
0
8
% H
% Ile:
0
0
0
8
0
62
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
62
0
0
8
8
0
0
16
0
0
8
0
0
0
77
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
54
8
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
62
0
8
0
0
0
0
8
85
0
0
% R
% Ser:
8
8
0
16
0
0
8
70
8
77
0
8
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
8
0
8
0
0
0
77
0
% T
% Val:
0
0
0
0
0
16
77
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _