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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
34.55
Human Site:
S527
Identified Species:
63.33
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
S527
N
A
I
K
Q
T
F
S
A
P
G
F
K
C
G
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
S527
N
A
I
K
Q
T
F
S
A
P
G
F
K
C
G
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
S527
N
A
V
K
Q
T
F
S
A
P
G
F
K
C
G
Dog
Lupus familis
XP_850664
607
68310
S527
N
A
V
R
Q
T
F
S
A
P
G
F
K
C
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
S527
N
A
V
K
Q
T
F
S
A
P
G
F
K
C
G
Rat
Rattus norvegicus
NP_001102279
607
67944
S527
N
A
I
K
Q
S
F
S
A
P
G
F
K
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
S527
N
A
I
K
Q
T
F
S
A
P
G
F
K
C
G
Chicken
Gallus gallus
XP_422568
607
67856
S527
G
A
V
K
Q
T
F
S
A
Q
G
F
K
C
G
Frog
Xenopus laevis
Q5FWQ6
415
45899
K336
V
Y
S
A
S
S
R
K
C
L
A
K
L
E
G
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
T251
A
G
K
A
T
G
E
T
S
P
S
R
Q
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
S523
L
R
K
N
Q
V
I
S
T
F
T
N
E
H
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
H497
L
R
T
F
Q
T
V
H
C
Y
S
A
E
N
Y
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
T500
L
R
T
N
Q
V
I
T
S
C
S
A
E
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
100
80
6.6
6.6
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
13.3
26.6
N.A.
20
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
62
0
16
0
0
0
0
62
0
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
16
8
0
0
0
62
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
24
8
0
% E
% Phe:
0
0
0
8
0
0
62
0
0
8
0
62
0
0
16
% F
% Gly:
8
8
0
0
0
8
0
0
0
0
62
0
0
8
70
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
31
0
0
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
54
0
0
0
8
0
0
0
8
62
0
0
% K
% Leu:
24
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
54
0
0
16
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% P
% Gln:
0
0
0
0
85
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
24
0
8
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
0
8
16
0
70
16
0
24
0
0
0
8
% S
% Thr:
0
0
16
0
8
62
0
16
8
0
8
0
0
0
0
% T
% Val:
8
0
31
0
0
16
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _