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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
30
Human Site:
S579
Identified Species:
55
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
S579
L
S
K
Q
H
S
S
S
I
N
A
V
A
W
S
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
S579
L
S
K
Q
H
S
S
S
I
N
A
V
A
W
S
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
S579
L
S
K
Q
H
S
S
S
I
N
A
V
A
W
S
Dog
Lupus familis
XP_850664
607
68310
S579
L
S
K
Q
H
G
S
S
I
N
A
V
A
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
S579
L
S
K
Q
H
S
S
S
I
N
A
V
A
W
A
Rat
Rattus norvegicus
NP_001102279
607
67944
S579
L
S
K
Q
H
S
S
S
I
N
A
V
A
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
S579
L
S
K
F
H
S
S
S
I
N
A
V
A
W
S
Chicken
Gallus gallus
XP_422568
607
67856
P579
L
A
K
H
H
S
S
P
I
N
A
V
A
W
S
Frog
Xenopus laevis
Q5FWQ6
415
45899
D388
Q
V
L
K
G
H
T
D
E
I
F
S
C
A
F
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
A303
E
N
A
E
V
P
S
A
C
A
D
V
R
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
T575
A
T
L
K
G
H
S
T
A
V
N
A
V
S
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
S549
E
K
Q
L
C
S
N
S
E
N
A
I
F
S
L
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
K552
E
K
Q
I
K
D
H
K
G
P
V
I
C
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
80
0
13.3
N.A.
6.6
N.A.
26.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
86.6
13.3
33.3
N.A.
26.6
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
8
8
8
70
8
62
8
16
% A
% Cys:
0
0
0
0
8
0
0
0
8
0
0
0
16
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% D
% Glu:
24
0
0
8
0
0
0
0
16
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
8
% F
% Gly:
0
0
0
0
16
8
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
8
62
16
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
62
8
0
16
0
0
0
% I
% Lys:
0
16
62
16
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
62
0
16
8
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
70
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
8
% P
% Gln:
8
0
16
47
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
54
0
0
0
62
77
62
0
0
0
8
0
16
54
% S
% Thr:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
0
8
8
70
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _