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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
33.64
Human Site:
T280
Identified Species:
61.67
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Dog
Lupus familis
XP_850664
607
68310
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Rat
Rattus norvegicus
NP_001102279
607
67944
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
T280
G
G
L
L
E
S
L
T
N
I
F
G
R
R
S
Chicken
Gallus gallus
XP_422568
607
67856
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Frog
Xenopus laevis
Q5FWQ6
415
45899
A99
I
L
P
L
T
N
V
A
F
N
K
S
G
S
S
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
V14
E
C
L
W
K
R
H
V
V
E
Q
L
K
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
G252
Q
F
V
G
G
L
I
G
D
E
D
F
D
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
K254
A
V
Q
D
I
T
D
K
D
T
K
L
E
E
M
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
S248
T
P
M
P
E
P
K
S
S
I
G
E
G
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
100
13.3
6.6
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
26.6
20
N.A.
26.6
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
54
0
8
0
16
0
8
0
8
0
0
% D
% Glu:
8
0
0
0
16
0
0
0
0
16
0
8
8
16
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
62
8
0
0
0
% F
% Gly:
62
62
0
8
8
0
0
8
0
0
8
62
16
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
62
0
0
70
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
8
8
0
0
16
0
8
0
8
% K
% Leu:
0
8
70
70
0
8
8
0
0
0
0
16
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
62
8
0
0
0
0
0
% N
% Pro:
0
8
8
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
62
70
8
% R
% Ser:
0
0
0
0
0
62
0
8
8
0
0
8
0
8
70
% S
% Thr:
8
0
0
0
8
8
0
62
0
8
0
0
0
0
0
% T
% Val:
0
8
8
0
0
0
8
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _