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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
22.12
Human Site:
T300
Identified Species:
40.56
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
T300
V
P
Q
D
N
V
D
T
H
P
G
S
G
K
E
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
T300
V
P
Q
D
N
V
D
T
H
P
G
S
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
T300
V
P
Q
D
N
V
D
T
H
P
G
S
G
K
E
Dog
Lupus familis
XP_850664
607
68310
T300
V
P
Q
D
N
V
D
T
H
P
G
S
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
T300
V
P
Q
D
I
M
D
T
H
P
A
S
G
K
D
Rat
Rattus norvegicus
NP_001102279
607
67944
T300
V
P
Q
D
V
V
D
T
H
P
A
S
G
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
A300
V
P
Q
D
T
M
G
A
R
S
G
S
R
K
E
Chicken
Gallus gallus
XP_422568
607
67856
P300
P
P
Q
D
N
A
E
P
H
P
G
A
S
K
E
Frog
Xenopus laevis
Q5FWQ6
415
45899
W119
Y
D
R
T
C
K
V
W
D
T
A
S
G
E
E
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
H34
Q
A
F
E
E
I
I
H
Q
Y
N
R
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
D272
M
E
A
I
G
L
D
D
N
E
Y
I
S
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
L274
D
T
N
S
N
G
D
L
L
L
G
D
S
V
P
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
S268
S
M
S
A
S
T
L
S
R
A
P
S
L
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
53.3
60
20
6.6
N.A.
6.6
N.A.
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
60
73.3
33.3
20
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
0
8
0
8
24
8
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
62
0
0
62
8
8
0
0
8
0
0
16
% D
% Glu:
0
8
0
8
8
0
8
0
0
8
0
0
0
8
62
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
8
8
0
0
0
54
0
47
0
0
% G
% His:
0
0
0
0
0
0
0
8
54
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
8
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
62
0
% K
% Leu:
0
0
0
0
0
8
8
8
8
8
0
0
16
8
0
% L
% Met:
8
8
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
47
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
62
0
0
0
0
0
8
0
54
8
0
0
8
16
% P
% Gln:
8
0
62
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
16
0
0
8
8
0
8
% R
% Ser:
8
0
8
8
8
0
0
8
0
8
0
70
31
0
0
% S
% Thr:
0
8
0
8
8
8
0
47
0
8
0
0
0
0
0
% T
% Val:
54
0
0
0
8
39
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _