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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L1
All Species:
32.73
Human Site:
T501
Identified Species:
60
UniProt:
Q676U5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q676U5
NP_060444.3
607
68265
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Rhesus Macaque
Macaca mulatta
XP_001114814
607
68295
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Dog
Lupus familis
XP_850664
607
68310
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0J2
607
68153
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Rat
Rattus norvegicus
NP_001102279
607
67944
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520939
607
68368
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Chicken
Gallus gallus
XP_422568
607
67856
T501
L
D
L
N
S
E
R
T
E
L
L
T
C
S
R
Frog
Xenopus laevis
Q5FWQ6
415
45899
T310
D
D
E
V
L
D
V
T
F
D
S
T
G
Q
L
Zebra Danio
Brachydanio rerio
NP_001017854
330
38008
A225
Q
K
E
L
A
D
A
A
K
E
P
L
P
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733313
604
67257
K497
I
T
S
L
D
L
S
K
D
C
N
Y
L
I
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19124
578
65468
M471
I
T
S
L
D
V
T
M
S
G
C
E
L
L
V
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
P474
V
T
S
L
D
L
S
P
D
R
Q
S
L
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
95.3
N.A.
94
93.9
N.A.
84.3
86.3
22.8
37.4
N.A.
38.3
N.A.
28.1
39
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97
97
N.A.
91
93.9
37
45.6
N.A.
60.9
N.A.
47.1
57.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
13.3
0
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
26.6
13.3
N.A.
13.3
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
62
0
8
% C
% Asp:
8
70
0
0
24
16
0
0
16
8
0
0
0
0
8
% D
% Glu:
0
0
16
0
0
62
0
0
62
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% I
% Lys:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
62
0
62
31
8
16
0
0
0
62
62
8
24
16
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
62
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
54
0
0
8
0
0
8
0
8
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
62
0
0
8
0
0
0
0
62
% R
% Ser:
0
0
24
0
8
0
16
0
8
0
8
62
0
62
0
% S
% Thr:
0
24
0
0
0
0
8
70
0
0
0
16
0
0
0
% T
% Val:
8
0
0
8
0
8
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _