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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3L3
All Species:
1.21
Human Site:
S133
Identified Species:
2.67
UniProt:
Q68CJ9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CJ9
NP_115996.1
461
49077
S133
Y
H
P
G
N
S
C
S
T
T
T
P
G
P
V
Chimpanzee
Pan troglodytes
XP_524059
461
49123
P133
Y
H
P
G
N
S
C
P
T
T
P
P
G
P
V
Rhesus Macaque
Macaca mulatta
XP_001118020
269
29178
Dog
Lupus familis
XP_542164
609
64987
L255
Y
H
P
G
P
P
C
L
A
G
G
P
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91XE9
479
52127
H117
A
N
T
V
A
R
C
H
T
R
E
Q
G
K
G
Rat
Rattus norvegicus
Q5FVM5
470
50844
H117
A
N
V
A
A
R
C
H
P
S
K
Q
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509261
401
43652
D88
D
G
I
L
R
H
V
D
L
E
G
S
D
W
T
Chicken
Gallus gallus
XP_425893
443
47494
L110
F
T
N
S
C
Q
V
L
T
H
P
G
G
T
G
Frog
Xenopus laevis
A2VD01
525
57606
A154
L
A
T
S
A
V
S
A
S
P
E
V
G
V
S
Zebra Danio
Brachydanio rerio
Q502F0
428
48228
T111
P
H
I
V
V
S
Q
T
Q
H
S
L
N
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
V119
S
H
E
G
E
G
H
V
T
D
L
T
L
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
55.3
58.1
N.A.
69.3
65.1
N.A.
53.5
55.3
27
41.6
N.A.
N.A.
N.A.
N.A.
32.3
Protein Similarity:
100
98.9
56.8
62.7
N.A.
75.7
74
N.A.
59.8
63.7
42.8
54.6
N.A.
N.A.
N.A.
N.A.
48.8
P-Site Identity:
100
86.6
0
53.3
N.A.
20
13.3
N.A.
0
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
86.6
0
53.3
N.A.
26.6
26.6
N.A.
0
20
20
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
10
28
0
0
10
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
10
0
0
10
10
0
% D
% Glu:
0
0
10
0
10
0
0
0
0
10
19
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
37
0
10
0
0
0
10
19
10
64
0
28
% G
% His:
0
46
0
0
0
10
10
19
0
19
0
0
0
0
0
% H
% Ile:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% K
% Leu:
10
0
0
10
0
0
0
19
10
0
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
19
10
0
19
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
10
0
28
0
10
10
0
10
10
10
19
28
0
28
0
% P
% Gln:
0
0
0
0
0
10
10
0
10
0
0
19
0
0
0
% Q
% Arg:
0
0
0
0
10
19
0
0
0
10
0
0
0
0
0
% R
% Ser:
10
0
0
19
0
28
10
10
10
10
10
10
0
0
10
% S
% Thr:
0
10
19
0
0
0
0
10
46
19
10
10
0
10
10
% T
% Val:
0
0
10
19
10
10
19
10
0
0
0
10
0
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _