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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HGSNAT All Species: 15.15
Human Site: S239 Identified Species: 37.04
UniProt: Q68CP4 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68CP4 NP_689632.2 663 73293 S239 E T D R L I N S E L G S P S R
Chimpanzee Pan troglodytes XP_519741 842 92473 S418 E T D R L I N S E L G S P S R
Rhesus Macaque Macaca mulatta XP_001115683 514 56665 A101 G K P S V A A A S V S T Q H G
Dog Lupus familis XP_539948 715 79848 S291 E T D R L I N S E L G S P G R
Cat Felis silvestris
Mouse Mus musculus Q3UDW8 656 72520 S234 E T D R L I N S E L G S P S R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516736 448 51090 S34 N L T V Y W L S D H C Y Q C L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139059 582 66255 R169 L R L R C S Q R L K N R M C H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572198 576 64305 Y163 C A W R Y Y R Y D E A T A A A
Honey Bee Apis mellifera XP_623715 567 64781 N154 I K G K L S P N N I Y D D L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001185505 642 72204 K227 I F C I L Y K K M C N S G S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.7 73 74.2 N.A. 79 N.A. N.A. 47 N.A. N.A. 41.7 N.A. 35.1 35.1 N.A. 36.5
Protein Similarity: 100 76.7 74.9 82 N.A. 85.9 N.A. N.A. 55.6 N.A. N.A. 58.6 N.A. 50.3 50.5 N.A. 54.7
P-Site Identity: 100 100 0 93.3 N.A. 100 N.A. N.A. 6.6 N.A. N.A. 6.6 N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 100 26.6 93.3 N.A. 100 N.A. N.A. 13.3 N.A. N.A. 6.6 N.A. 26.6 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 10 10 0 0 10 0 10 10 10 % A
% Cys: 10 0 10 0 10 0 0 0 0 10 10 0 0 20 0 % C
% Asp: 0 0 40 0 0 0 0 0 20 0 0 10 10 0 10 % D
% Glu: 40 0 0 0 0 0 0 0 40 10 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 0 0 0 0 40 0 10 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 10 % H
% Ile: 20 0 0 10 0 40 0 0 0 10 0 0 0 0 10 % I
% Lys: 0 20 0 10 0 0 10 10 0 10 0 0 0 0 0 % K
% Leu: 10 10 10 0 60 0 10 0 10 40 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % M
% Asn: 10 0 0 0 0 0 40 10 10 0 20 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 10 0 0 0 0 0 40 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 20 0 0 % Q
% Arg: 0 10 0 60 0 0 10 10 0 0 0 10 0 0 40 % R
% Ser: 0 0 0 10 0 20 0 50 10 0 10 50 0 40 0 % S
% Thr: 0 40 10 0 0 0 0 0 0 0 0 20 0 0 0 % T
% Val: 0 0 0 10 10 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 20 20 0 10 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _