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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HGSNAT All Species: 16.36
Human Site: S243 Identified Species: 40
UniProt: Q68CP4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68CP4 NP_689632.2 663 73293 S243 L I N S E L G S P S R T D P L
Chimpanzee Pan troglodytes XP_519741 842 92473 S422 L I N S E L G S P S R T D P L
Rhesus Macaque Macaca mulatta XP_001115683 514 56665 T105 V A A A S V S T Q H G A I L Q
Dog Lupus familis XP_539948 715 79848 S295 L I N S E L G S P G R A G S I
Cat Felis silvestris
Mouse Mus musculus Q3UDW8 656 72520 S238 L I N S E L G S P S R A D P L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516736 448 51090 Y38 Y W L S D H C Y Q C L Y Q V L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139059 582 66255 R173 C S Q R L K N R M C H H G S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572198 576 64305 T167 Y Y R Y D E A T A A A D S I G
Honey Bee Apis mellifera XP_623715 567 64781 D158 L S P N N I Y D D L D R L Q E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001185505 642 72204 S231 L Y K K M C N S G S I N R F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.7 73 74.2 N.A. 79 N.A. N.A. 47 N.A. N.A. 41.7 N.A. 35.1 35.1 N.A. 36.5
Protein Similarity: 100 76.7 74.9 82 N.A. 85.9 N.A. N.A. 55.6 N.A. N.A. 58.6 N.A. 50.3 50.5 N.A. 54.7
P-Site Identity: 100 100 0 66.6 N.A. 93.3 N.A. N.A. 13.3 N.A. N.A. 0 N.A. 0 6.6 N.A. 26.6
P-Site Similarity: 100 100 26.6 73.3 N.A. 93.3 N.A. N.A. 20 N.A. N.A. 0 N.A. 20 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 10 0 10 10 10 30 0 0 0 % A
% Cys: 10 0 0 0 0 10 10 0 0 20 0 0 0 0 0 % C
% Asp: 0 0 0 0 20 0 0 10 10 0 10 10 30 0 0 % D
% Glu: 0 0 0 0 40 10 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 40 0 10 10 10 0 20 0 10 % G
% His: 0 0 0 0 0 10 0 0 0 10 10 10 0 0 0 % H
% Ile: 0 40 0 0 0 10 0 0 0 0 10 0 10 10 10 % I
% Lys: 0 0 10 10 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 60 0 10 0 10 40 0 0 0 10 10 0 10 10 50 % L
% Met: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 40 10 10 0 20 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 40 0 0 0 0 30 0 % P
% Gln: 0 0 10 0 0 0 0 0 20 0 0 0 10 10 20 % Q
% Arg: 0 0 10 10 0 0 0 10 0 0 40 10 10 0 0 % R
% Ser: 0 20 0 50 10 0 10 50 0 40 0 0 10 20 0 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 0 20 0 0 0 % T
% Val: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 20 0 10 0 0 10 10 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _