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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C1orf175 All Species: 1.82
Human Site: S378 Identified Species: 6.67
UniProt: Q68CQ1 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68CQ1 NP_001034553.2 1323 145666 S378 E E N L E S W S E M A S I K V
Chimpanzee Pan troglodytes XP_513425 565 61537
Rhesus Macaque Macaca mulatta XP_001093209 1052 119487 K190 E L K G E L E K L T F L G S L
Dog Lupus familis XP_853181 702 79801
Cat Felis silvestris
Mouse Mus musculus A2AVR2 1279 141692 A379 E D V K V N E A E K R N H D N
Rat Rattus norvegicus A2RUW0 1122 123840 S260 S V N V T S N S Q P R S G L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414283 887 100344 Q25 C R P Q A E A Q K L S F L A S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.7 26.6 45.4 N.A. 70.1 60.5 N.A. N.A. 20.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 42.3 43.1 49.3 N.A. 80.2 69.6 N.A. N.A. 36.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 13.3 0 N.A. 13.3 26.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 20 0 N.A. 40 40 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 15 15 0 0 15 0 0 15 0 % A
% Cys: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 0 0 0 0 0 0 0 0 15 0 % D
% Glu: 43 15 0 0 29 15 29 0 29 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 15 15 0 0 0 % F
% Gly: 0 0 0 15 0 0 0 0 0 0 0 0 29 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 0 0 15 15 0 0 0 15 15 15 0 0 0 15 0 % K
% Leu: 0 15 0 15 0 15 0 0 15 15 0 15 15 15 15 % L
% Met: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % M
% Asn: 0 0 29 0 0 15 15 0 0 0 0 15 0 0 29 % N
% Pro: 0 0 15 0 0 0 0 0 0 15 0 0 0 0 0 % P
% Gln: 0 0 0 15 0 0 0 15 15 0 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 29 0 0 0 0 % R
% Ser: 15 0 0 0 0 29 0 29 0 0 15 29 0 15 15 % S
% Thr: 0 0 0 0 15 0 0 0 0 15 0 0 0 0 0 % T
% Val: 0 15 15 15 15 0 0 0 0 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _