Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEF All Species: 10.3
Human Site: S167 Identified Species: 18.89
UniProt: Q68CQ4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68CQ4 NP_055203.4 756 87055 S167 A K H E S L F S L E T N F L E
Chimpanzee Pan troglodytes XP_525053 756 87125 S167 A K H E S L F S L E T N F L E
Rhesus Macaque Macaca mulatta XP_001109922 755 86704 S166 A K H E S L F S L E T N F L E
Dog Lupus familis XP_547394 639 73475 V103 T H Q L K W P V L G Q L V F S
Cat Felis silvestris
Mouse Mus musculus Q8BTT6 772 88799 Q167 E E P P G V S Q K S S E E F T
Rat Rattus norvegicus Q5M9G7 763 87806 H167 E E F T D V K H E S L F S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509371 772 89238 V169 A E E D F T D V K H E S Q F S
Chicken Gallus gallus Q5ZLG3 772 88932 T165 R G A I E E F T D V K H E A E
Frog Xenopus laevis NP_001091284 767 88492 D168 E D A G E F T D A K H E S K F
Zebra Danio Brachydanio rerio Q6PEH4 753 86784 K165 E G E F T D K K N E A A F C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611851 700 81542 N164 R N W S A L G N V R F D I P R
Honey Bee Apis mellifera XP_395073 700 81460 I163 A V S N V P Q I M E T Q K I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40498 721 83973 D175 Q V P E K F V D K L S N A F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.7 78 N.A. 86.2 87.8 N.A. 74.3 68.9 68 54.5 N.A. 35.3 42.2 N.A. N.A.
Protein Similarity: 100 99.7 98.4 81.3 N.A. 91.1 93.3 N.A. 85.6 81.3 82 71 N.A. 56.3 62.8 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 0 13.3 N.A. 6.6 13.3 0 13.3 N.A. 6.6 20 N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 20 26.6 N.A. 26.6 26.6 6.6 20 N.A. 33.3 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 16 0 8 0 0 0 8 0 8 8 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 8 0 8 8 8 8 16 8 0 0 8 0 0 0 % D
% Glu: 31 24 16 31 16 8 0 0 8 39 8 16 16 0 39 % E
% Phe: 0 0 8 8 8 16 31 0 0 0 8 8 31 31 8 % F
% Gly: 0 16 0 8 8 0 8 0 0 8 0 0 0 0 0 % G
% His: 0 8 24 0 0 0 0 8 0 8 8 8 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 0 0 8 8 0 % I
% Lys: 0 24 0 0 16 0 16 8 24 8 8 0 8 8 8 % K
% Leu: 0 0 0 8 0 31 0 0 31 8 8 8 0 31 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 8 8 0 0 31 0 0 0 % N
% Pro: 0 0 16 8 0 8 8 0 0 0 0 0 0 8 0 % P
% Gln: 8 0 8 0 0 0 8 8 0 0 8 8 8 0 0 % Q
% Arg: 16 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % R
% Ser: 0 0 8 8 24 0 8 24 0 16 16 8 16 0 16 % S
% Thr: 8 0 0 8 8 8 8 8 0 0 31 0 0 0 16 % T
% Val: 0 16 0 0 8 16 8 16 8 8 0 0 8 0 0 % V
% Trp: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _