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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF
All Species:
10.3
Human Site:
S167
Identified Species:
18.89
UniProt:
Q68CQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CQ4
NP_055203.4
756
87055
S167
A
K
H
E
S
L
F
S
L
E
T
N
F
L
E
Chimpanzee
Pan troglodytes
XP_525053
756
87125
S167
A
K
H
E
S
L
F
S
L
E
T
N
F
L
E
Rhesus Macaque
Macaca mulatta
XP_001109922
755
86704
S166
A
K
H
E
S
L
F
S
L
E
T
N
F
L
E
Dog
Lupus familis
XP_547394
639
73475
V103
T
H
Q
L
K
W
P
V
L
G
Q
L
V
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTT6
772
88799
Q167
E
E
P
P
G
V
S
Q
K
S
S
E
E
F
T
Rat
Rattus norvegicus
Q5M9G7
763
87806
H167
E
E
F
T
D
V
K
H
E
S
L
F
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509371
772
89238
V169
A
E
E
D
F
T
D
V
K
H
E
S
Q
F
S
Chicken
Gallus gallus
Q5ZLG3
772
88932
T165
R
G
A
I
E
E
F
T
D
V
K
H
E
A
E
Frog
Xenopus laevis
NP_001091284
767
88492
D168
E
D
A
G
E
F
T
D
A
K
H
E
S
K
F
Zebra Danio
Brachydanio rerio
Q6PEH4
753
86784
K165
E
G
E
F
T
D
K
K
N
E
A
A
F
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611851
700
81542
N164
R
N
W
S
A
L
G
N
V
R
F
D
I
P
R
Honey Bee
Apis mellifera
XP_395073
700
81460
I163
A
V
S
N
V
P
Q
I
M
E
T
Q
K
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40498
721
83973
D175
Q
V
P
E
K
F
V
D
K
L
S
N
A
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
78
N.A.
86.2
87.8
N.A.
74.3
68.9
68
54.5
N.A.
35.3
42.2
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
81.3
N.A.
91.1
93.3
N.A.
85.6
81.3
82
71
N.A.
56.3
62.8
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
0
13.3
N.A.
6.6
13.3
0
13.3
N.A.
6.6
20
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
20
26.6
N.A.
26.6
26.6
6.6
20
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
16
0
8
0
0
0
8
0
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
8
8
8
8
16
8
0
0
8
0
0
0
% D
% Glu:
31
24
16
31
16
8
0
0
8
39
8
16
16
0
39
% E
% Phe:
0
0
8
8
8
16
31
0
0
0
8
8
31
31
8
% F
% Gly:
0
16
0
8
8
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
8
24
0
0
0
0
8
0
8
8
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
0
0
8
8
0
% I
% Lys:
0
24
0
0
16
0
16
8
24
8
8
0
8
8
8
% K
% Leu:
0
0
0
8
0
31
0
0
31
8
8
8
0
31
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
8
8
0
0
31
0
0
0
% N
% Pro:
0
0
16
8
0
8
8
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
8
0
0
0
8
8
0
0
8
8
8
0
0
% Q
% Arg:
16
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
0
8
8
24
0
8
24
0
16
16
8
16
0
16
% S
% Thr:
8
0
0
8
8
8
8
8
0
0
31
0
0
0
16
% T
% Val:
0
16
0
0
8
16
8
16
8
8
0
0
8
0
0
% V
% Trp:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _