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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF
All Species:
22.12
Human Site:
S266
Identified Species:
40.56
UniProt:
Q68CQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CQ4
NP_055203.4
756
87055
S266
K
T
N
S
Q
F
L
S
G
P
Q
K
S
S
S
Chimpanzee
Pan troglodytes
XP_525053
756
87125
S266
K
T
N
S
Q
F
L
S
G
P
Q
K
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001109922
755
86704
S265
K
T
N
S
P
F
L
S
G
P
Q
K
S
S
S
Dog
Lupus familis
XP_547394
639
73475
L195
E
I
R
H
V
Y
C
L
H
A
I
N
H
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTT6
772
88799
S282
K
T
N
S
Q
F
L
S
G
P
Q
K
S
N
S
Rat
Rattus norvegicus
Q5M9G7
763
87806
S271
K
T
N
S
Q
F
L
S
G
P
G
P
Q
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509371
772
89238
S283
Q
T
N
R
Q
F
L
S
A
A
G
K
Q
K
G
Chicken
Gallus gallus
Q5ZLG3
772
88932
S282
V
N
K
H
Y
L
S
S
A
S
K
P
S
D
S
Frog
Xenopus laevis
NP_001091284
767
88492
F278
W
P
K
V
N
S
P
F
L
S
A
P
N
E
Q
Zebra Danio
Brachydanio rerio
Q6PEH4
753
86784
N263
E
A
N
W
H
L
L
N
L
P
F
G
A
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611851
700
81542
R256
L
N
H
M
L
K
V
R
S
L
I
L
R
N
N
Honey Bee
Apis mellifera
XP_395073
700
81460
T255
R
F
V
Y
C
L
H
T
I
N
H
V
L
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40498
721
83973
Y268
Y
K
D
I
L
Y
E
Y
D
S
Y
E
K
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
78
N.A.
86.2
87.8
N.A.
74.3
68.9
68
54.5
N.A.
35.3
42.2
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
81.3
N.A.
91.1
93.3
N.A.
85.6
81.3
82
71
N.A.
56.3
62.8
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
93.3
73.3
N.A.
46.6
20
0
20
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
100
73.3
N.A.
53.3
26.6
6.6
53.3
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
16
16
8
0
8
8
0
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
0
0
0
0
16
0
% D
% Glu:
16
0
0
0
0
0
8
0
0
0
0
8
0
8
8
% E
% Phe:
0
8
0
0
0
47
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
39
0
16
8
0
0
8
% G
% His:
0
0
8
16
8
0
8
0
8
0
8
0
8
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
8
0
16
0
0
0
0
% I
% Lys:
39
8
16
0
0
8
0
0
0
0
8
39
8
24
0
% K
% Leu:
8
0
0
0
16
24
54
8
16
8
0
8
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
54
0
8
0
0
8
0
8
0
8
8
16
8
% N
% Pro:
0
8
0
0
8
0
8
0
0
47
0
24
0
0
0
% P
% Gln:
8
0
0
0
39
0
0
0
0
0
31
0
16
0
8
% Q
% Arg:
8
0
8
8
0
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
39
0
8
8
54
8
24
0
0
39
24
47
% S
% Thr:
0
47
0
0
0
0
0
8
0
0
0
0
0
0
16
% T
% Val:
8
0
8
8
8
0
8
0
0
0
0
8
0
8
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
16
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _