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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF
All Species:
36.97
Human Site:
Y439
Identified Species:
67.78
UniProt:
Q68CQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CQ4
NP_055203.4
756
87055
Y439
L
Q
R
S
I
R
L
Y
A
P
F
Y
S
S
D
Chimpanzee
Pan troglodytes
XP_525053
756
87125
Y439
L
Q
R
S
I
R
L
Y
A
P
F
Y
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001109922
755
86704
Y438
L
Q
R
S
I
R
L
Y
A
P
F
Y
S
S
D
Dog
Lupus familis
XP_547394
639
73475
G346
R
T
I
I
G
A
E
G
E
K
K
R
D
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTT6
772
88799
Y455
L
Q
R
S
I
R
L
Y
A
P
F
Y
S
S
D
Rat
Rattus norvegicus
Q5M9G7
763
87806
Y446
L
Q
R
S
I
R
L
Y
A
P
F
Y
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509371
772
89238
Y455
L
Q
K
G
I
R
L
Y
A
P
F
Y
S
S
D
Chicken
Gallus gallus
Q5ZLG3
772
88932
Y454
L
Q
K
S
M
R
L
Y
A
P
F
Y
S
S
D
Frog
Xenopus laevis
NP_001091284
767
88492
Y449
L
Q
K
S
M
R
L
Y
S
P
F
Y
S
S
D
Zebra Danio
Brachydanio rerio
Q6PEH4
753
86784
Y432
L
R
H
S
M
R
L
Y
A
P
F
Y
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611851
700
81542
E407
R
M
L
V
T
D
K
E
S
D
F
D
F
L
N
Honey Bee
Apis mellifera
XP_395073
700
81460
A406
L
I
G
A
E
G
E
A
D
R
D
Y
D
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40498
721
83973
T421
I
Q
M
I
L
E
N
T
D
K
K
K
R
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
78
N.A.
86.2
87.8
N.A.
74.3
68.9
68
54.5
N.A.
35.3
42.2
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
81.3
N.A.
91.1
93.3
N.A.
85.6
81.3
82
71
N.A.
56.3
62.8
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
86.6
86.6
80
80
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
62
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
16
8
8
8
16
0
85
% D
% Glu:
0
0
0
0
8
8
16
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
77
0
8
8
0
% F
% Gly:
0
0
8
8
8
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
16
47
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
24
0
0
0
8
0
0
16
16
8
0
0
0
% K
% Leu:
77
0
8
0
8
0
70
0
0
0
0
0
0
8
8
% L
% Met:
0
8
8
0
24
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% P
% Gln:
0
70
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
16
8
39
0
0
70
0
0
0
8
0
8
8
0
0
% R
% Ser:
0
0
0
62
0
0
0
0
16
0
0
0
70
70
0
% S
% Thr:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
77
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _