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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF
All Species:
34.85
Human Site:
Y644
Identified Species:
63.89
UniProt:
Q68CQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CQ4
NP_055203.4
756
87055
Y644
N
F
T
H
I
C
E
Y
T
Q
K
S
G
V
S
Chimpanzee
Pan troglodytes
XP_525053
756
87125
Y644
N
F
T
H
I
C
E
Y
T
Q
K
S
G
V
S
Rhesus Macaque
Macaca mulatta
XP_001109922
755
86704
Y643
N
F
T
H
I
C
E
Y
T
Q
K
S
G
V
S
Dog
Lupus familis
XP_547394
639
73475
R535
T
P
K
S
G
I
S
R
A
R
H
F
F
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTT6
772
88799
Y660
N
F
T
H
I
C
E
Y
T
Q
K
S
G
I
S
Rat
Rattus norvegicus
Q5M9G7
763
87806
Y651
N
F
T
H
I
C
E
Y
T
Q
R
S
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509371
772
89238
Y660
N
F
T
Q
I
C
E
Y
S
K
R
S
D
I
S
Chicken
Gallus gallus
Q5ZLG3
772
88932
Y659
N
F
T
H
I
C
E
Y
T
K
K
A
G
I
C
Frog
Xenopus laevis
NP_001091284
767
88492
Y654
N
F
A
H
I
C
E
Y
T
N
K
P
G
I
S
Zebra Danio
Brachydanio rerio
Q6PEH4
753
86784
Y636
S
F
A
N
I
S
E
Y
S
Q
R
S
E
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611851
700
81542
D596
E
K
I
S
R
A
R
D
I
F
F
H
S
G
A
Honey Bee
Apis mellifera
XP_395073
700
81460
D596
A
K
I
A
R
A
R
D
M
F
F
H
S
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40498
721
83973
S611
F
G
D
I
N
E
Y
S
S
Q
R
Q
L
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
78
N.A.
86.2
87.8
N.A.
74.3
68.9
68
54.5
N.A.
35.3
42.2
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
81.3
N.A.
91.1
93.3
N.A.
85.6
81.3
82
71
N.A.
56.3
62.8
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
60
73.3
73.3
53.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
86.6
93.3
80
80
N.A.
6.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
0
16
0
0
8
0
0
8
0
0
24
% A
% Cys:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
0
0
0
0
16
0
0
0
0
8
8
0
% D
% Glu:
8
0
0
0
0
8
70
0
0
0
0
0
8
0
0
% E
% Phe:
8
70
0
0
0
0
0
0
0
16
16
8
8
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
0
0
0
0
54
8
0
% G
% His:
0
0
0
54
0
0
0
0
0
0
8
16
0
0
0
% H
% Ile:
0
0
16
8
70
8
0
0
8
0
0
0
0
31
0
% I
% Lys:
0
16
8
0
0
0
0
0
0
16
47
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
62
0
0
8
8
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
54
0
8
0
0
8
% Q
% Arg:
0
0
0
0
16
0
16
8
0
8
31
0
0
0
0
% R
% Ser:
8
0
0
16
0
8
8
8
24
0
0
54
16
0
62
% S
% Thr:
8
0
54
0
0
0
0
0
54
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _