KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF
All Species:
30.3
Human Site:
Y72
Identified Species:
55.56
UniProt:
Q68CQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CQ4
NP_055203.4
756
87055
Y72
E
P
Q
Q
V
S
G
Y
H
R
L
L
A
T
L
Chimpanzee
Pan troglodytes
XP_525053
756
87125
Y72
E
P
E
Q
V
S
G
Y
H
R
L
L
A
T
L
Rhesus Macaque
Macaca mulatta
XP_001109922
755
86704
G71
S
E
P
E
Q
V
S
G
Y
H
K
L
L
A
T
Dog
Lupus familis
XP_547394
639
73475
E8
M
E
K
E
T
T
A
E
S
T
K
V
Q
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTT6
772
88799
Y72
E
Q
E
H
V
S
G
Y
H
R
L
L
A
T
L
Rat
Rattus norvegicus
Q5M9G7
763
87806
Y72
E
Q
E
H
V
S
G
Y
H
R
L
L
A
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509371
772
89238
Y74
E
S
E
Q
V
S
G
Y
H
K
L
L
A
T
L
Chicken
Gallus gallus
Q5ZLG3
772
88932
Y70
E
V
E
Q
V
S
V
Y
H
K
L
L
A
T
L
Frog
Xenopus laevis
NP_001091284
767
88492
Y73
E
P
E
Q
V
N
M
Y
H
Q
L
L
A
T
L
Zebra Danio
Brachydanio rerio
Q6PEH4
753
86784
Y70
D
A
E
Q
P
S
A
Y
Q
K
L
L
S
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611851
700
81542
V69
L
P
E
I
Q
D
D
V
D
E
T
E
F
Y
K
Honey Bee
Apis mellifera
XP_395073
700
81460
Q68
F
S
N
T
T
N
L
Q
M
T
A
I
D
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40498
721
83973
Y80
E
G
K
K
E
K
V
Y
D
A
L
L
T
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
78
N.A.
86.2
87.8
N.A.
74.3
68.9
68
54.5
N.A.
35.3
42.2
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
81.3
N.A.
91.1
93.3
N.A.
85.6
81.3
82
71
N.A.
56.3
62.8
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
0
N.A.
80
80
N.A.
80
73.3
73.3
40
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
20
26.6
N.A.
86.6
86.6
N.A.
93.3
86.6
93.3
73.3
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
16
0
0
8
8
0
54
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
16
0
0
0
8
0
0
% D
% Glu:
62
16
62
16
8
0
0
8
0
8
0
8
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
39
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
16
0
0
0
0
54
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
16
8
0
8
0
0
0
24
16
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
8
0
0
0
70
77
8
0
62
% L
% Met:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
31
8
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
8
47
16
0
0
8
8
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% R
% Ser:
8
16
0
0
0
54
8
0
8
0
0
0
8
8
8
% S
% Thr:
0
0
0
8
16
8
0
0
0
16
8
0
8
62
8
% T
% Val:
0
8
0
0
54
8
16
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _