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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF
All Species:
28.79
Human Site:
Y724
Identified Species:
52.78
UniProt:
Q68CQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68CQ4
NP_055203.4
756
87055
Y724
C
T
V
L
Y
S
K
Y
D
A
Q
R
L
A
A
Chimpanzee
Pan troglodytes
XP_525053
756
87125
Y724
C
T
V
L
Y
S
R
Y
D
A
Q
R
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001109922
755
86704
Y723
C
T
V
L
Y
S
K
Y
D
A
Q
R
L
A
A
Dog
Lupus familis
XP_547394
639
73475
A613
R
Y
D
A
Q
R
L
A
A
V
V
G
V
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTT6
772
88799
Y740
C
T
V
L
Y
S
K
Y
D
A
Q
R
L
A
A
Rat
Rattus norvegicus
Q5M9G7
763
87806
Y731
C
T
V
L
Y
S
K
Y
D
A
Q
R
L
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509371
772
89238
F740
C
T
A
L
Y
S
K
F
D
A
Q
R
L
A
A
Chicken
Gallus gallus
Q5ZLG3
772
88932
Y739
C
T
V
L
Y
S
K
Y
D
A
Q
K
L
A
A
Frog
Xenopus laevis
NP_001091284
767
88492
Y734
C
T
V
L
Y
S
K
Y
D
A
Q
R
L
A
A
Zebra Danio
Brachydanio rerio
Q6PEH4
753
86784
S716
F
T
C
T
A
L
Y
S
R
Y
D
V
H
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611851
700
81542
L674
T
K
Y
D
L
L
S
L
S
N
I
V
G
S
E
Honey Bee
Apis mellifera
XP_395073
700
81460
L674
C
K
Y
D
I
M
Q
L
S
A
I
V
G
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40498
721
83973
Y690
I
S
T
V
R
C
I
Y
S
K
L
D
G
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
78
N.A.
86.2
87.8
N.A.
74.3
68.9
68
54.5
N.A.
35.3
42.2
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
81.3
N.A.
91.1
93.3
N.A.
85.6
81.3
82
71
N.A.
56.3
62.8
N.A.
N.A.
P-Site Identity:
100
93.3
100
0
N.A.
100
100
N.A.
86.6
93.3
100
6.6
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
100
100
6.6
N.A.
6.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
8
8
70
0
0
0
62
62
% A
% Cys:
70
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
0
0
0
0
62
0
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
24
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
8
0
8
0
0
0
16
0
0
0
0
% I
% Lys:
0
16
0
0
0
0
54
0
0
8
0
8
0
0
0
% K
% Leu:
0
0
0
62
8
16
8
16
0
0
8
0
62
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
62
0
0
0
8
% Q
% Arg:
8
0
0
0
8
8
8
0
8
0
0
54
0
8
8
% R
% Ser:
0
8
0
0
0
62
8
8
24
0
0
0
0
8
8
% S
% Thr:
8
70
8
8
0
0
0
0
0
0
0
0
0
16
0
% T
% Val:
0
0
54
8
0
0
0
0
0
8
8
24
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
16
0
62
0
8
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _