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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
18.48
Human Site:
S252
Identified Species:
33.89
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
S252
G
S
G
D
R
H
P
S
S
K
G
M
P
L
P
Chimpanzee
Pan troglodytes
XP_508321
684
75407
S252
G
S
G
D
R
H
P
S
S
K
G
M
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
S252
G
S
G
D
R
H
P
S
S
K
G
M
P
L
P
Dog
Lupus familis
XP_534086
793
86791
S363
T
K
L
S
K
H
P
S
S
R
G
T
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
A251
G
A
G
D
R
Q
L
A
S
K
G
L
P
F
P
Rat
Rattus norvegicus
XP_002725626
681
74519
P251
G
A
G
D
R
Q
P
P
S
K
G
L
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
N204
K
S
A
P
P
P
M
N
F
S
D
L
L
R
L
Chicken
Gallus gallus
XP_421015
633
66869
L209
E
L
R
E
R
E
Y
L
E
R
K
N
K
R
V
Frog
Xenopus laevis
Q6NU13
800
83727
S356
G
S
S
E
K
P
G
S
S
S
G
K
P
M
G
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
T213
K
T
E
E
R
L
R
T
A
E
E
I
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
R176
K
A
A
I
T
R
E
R
E
E
A
K
G
N
T
Honey Bee
Apis mellifera
XP_395689
579
67372
Y174
Y
N
Q
L
M
S
K
Y
N
N
T
S
S
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
T207
K
K
M
A
N
G
N
T
R
H
N
I
P
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
100
53.3
N.A.
60
66.6
N.A.
6.6
6.6
40
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
66.6
N.A.
80
80
N.A.
20
20
60
46.6
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
16
8
0
0
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
39
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
8
24
0
8
8
0
16
16
8
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
47
0
39
0
0
8
8
0
0
0
54
0
8
0
8
% G
% His:
0
0
0
0
0
31
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
0
% I
% Lys:
31
16
0
0
16
0
8
0
0
39
8
16
8
0
16
% K
% Leu:
0
8
8
8
0
8
8
8
0
0
0
24
8
31
16
% L
% Met:
0
0
8
0
8
0
8
0
0
0
0
24
0
8
0
% M
% Asn:
0
8
0
0
8
0
8
8
8
8
8
8
0
8
0
% N
% Pro:
0
0
0
8
8
16
39
8
0
0
0
0
62
8
47
% P
% Gln:
0
0
8
0
0
16
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
54
8
8
8
8
16
0
0
8
16
0
% R
% Ser:
0
39
8
8
0
8
0
39
54
16
0
8
8
0
0
% S
% Thr:
8
8
0
0
8
0
0
16
0
0
8
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _