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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND2C
All Species:
23.03
Human Site:
T216
Identified Species:
63.33
UniProt:
Q68D51
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D51
NP_940861.3
928
106865
T216
P
L
P
K
P
R
R
T
F
R
Y
L
S
E
S
Chimpanzee
Pan troglodytes
XP_524806
928
106789
T216
P
L
P
K
P
R
R
T
F
R
Y
L
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001103844
1137
126534
S378
S
Q
R
L
P
S
K
S
S
P
D
P
A
V
N
Dog
Lupus familis
XP_540246
1006
114451
T218
P
L
P
K
P
R
R
T
F
R
Y
L
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9P8
914
103919
T206
P
L
P
K
P
R
R
T
F
R
Y
L
S
E
S
Rat
Rattus norvegicus
XP_001067655
923
105695
T213
P
L
P
K
P
R
R
T
F
R
Y
L
S
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507742
942
107973
E229
R
T
F
R
Y
L
S
E
I
D
S
V
P
F
K
Chicken
Gallus gallus
XP_001234021
863
98211
E193
L
E
A
V
E
Q
E
E
K
L
A
A
V
P
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919086
920
104188
T210
P
P
P
K
P
Q
R
T
F
Q
Y
K
G
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
40.1
83.5
N.A.
83.1
82.7
N.A.
80.8
63.5
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
55.3
87.2
N.A.
89.2
89.2
N.A.
89.2
73.1
N.A.
62.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
0
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
13.3
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
0
12
12
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% D
% Glu:
0
12
0
0
12
0
12
23
0
0
0
0
0
56
0
% E
% Phe:
0
0
12
0
0
0
0
0
67
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
67
0
0
12
0
12
0
0
12
0
0
12
% K
% Leu:
12
56
0
12
0
12
0
0
0
12
0
56
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
67
12
67
0
78
0
0
0
0
12
0
12
12
12
12
% P
% Gln:
0
12
0
0
0
23
0
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
12
12
0
56
67
0
0
56
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
12
12
12
12
0
12
0
56
0
67
% S
% Thr:
0
12
0
0
0
0
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
12
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _