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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF43
All Species:
12.73
Human Site:
T539
Identified Species:
46.67
UniProt:
Q68DV7
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68DV7
NP_060233.3
783
85722
T539
S
L
D
S
V
V
P
T
G
E
T
Q
V
S
S
Chimpanzee
Pan troglodytes
XP_511907
783
85720
T539
S
L
D
S
V
V
P
T
G
E
T
Q
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001106506
783
85794
T539
S
L
D
S
V
V
P
T
G
E
T
Q
V
S
S
Dog
Lupus familis
XP_548234
780
85420
T539
S
L
D
S
V
V
P
T
G
E
A
Q
A
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCP0
784
86285
R539
S
L
D
S
V
V
P
R
G
E
T
Q
V
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515498
556
60307
L327
L
S
S
D
Y
D
P
L
V
Y
C
S
P
E
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499473
487
54928
I258
T
A
L
T
K
M
E
I
R
S
F
Q
K
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.3
85.9
N.A.
81.8
N.A.
N.A.
47.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
100
99.6
97.5
90.5
N.A.
87.2
N.A.
N.A.
54
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
0
15
0
15
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
72
15
0
15
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
15
0
0
72
0
0
0
29
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
15
0
0
0
0
0
0
0
15
0
15
% K
% Leu:
15
72
15
0
0
0
0
15
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
86
0
0
0
0
0
15
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
86
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
15
15
0
0
0
0
0
0
% R
% Ser:
72
15
15
72
0
0
0
0
0
15
0
15
0
58
72
% S
% Thr:
15
0
0
15
0
0
0
58
0
0
58
0
0
0
0
% T
% Val:
0
0
0
0
72
72
0
0
15
0
0
0
58
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _