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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMPD2
All Species:
6.06
Human Site:
T253
Identified Species:
16.67
UniProt:
Q68DX3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68DX3
NP_001017929.1
1309
144268
T253
E
P
H
W
S
T
L
T
H
S
H
C
S
L
L
Chimpanzee
Pan troglodytes
XP_001135868
1309
144360
T253
E
P
H
W
S
T
S
T
H
S
H
C
S
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543895
1454
159917
A244
V
P
G
L
S
T
P
A
H
S
H
H
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64512
2453
270316
G462
Q
Y
E
T
S
L
E
G
N
L
I
N
Q
D
I
Rat
Rattus norvegicus
NP_001094259
2455
270426
G462
Q
Y
E
T
S
L
E
G
S
L
I
N
Q
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507538
831
93245
Chicken
Gallus gallus
XP_421649
1389
154123
T279
P
V
C
V
S
V
S
T
E
P
L
A
A
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664234
2180
241992
R246
K
T
W
S
L
K
S
R
P
S
Q
T
T
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198924
1478
165815
Y375
E
S
A
R
Q
G
S
Y
H
P
D
Q
Y
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
51.7
N.A.
23.4
23.9
N.A.
25.5
47
N.A.
25
N.A.
N.A.
N.A.
N.A.
20.7
Protein Similarity:
100
99.3
N.A.
62.1
N.A.
35
35.1
N.A.
39.5
62.8
N.A.
37.3
N.A.
N.A.
N.A.
N.A.
37
P-Site Identity:
100
93.3
N.A.
53.3
N.A.
6.6
6.6
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
N.A.
53.3
N.A.
26.6
20
N.A.
0
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
12
0
0
0
12
12
0
12
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
23
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% D
% Glu:
34
0
23
0
0
0
23
0
12
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
12
0
23
0
0
0
0
0
0
12
% G
% His:
0
0
23
0
0
0
0
0
45
0
34
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
12
% I
% Lys:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
12
23
12
0
0
23
12
0
0
34
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
23
0
0
0
% N
% Pro:
12
34
0
0
0
0
12
0
12
23
0
0
0
0
0
% P
% Gln:
23
0
0
0
12
0
0
0
0
0
12
12
23
0
12
% Q
% Arg:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
12
67
0
45
0
12
45
0
0
34
23
0
% S
% Thr:
0
12
0
23
0
34
0
34
0
0
0
12
12
0
0
% T
% Val:
12
12
0
12
0
12
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
12
23
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
23
0
0
0
0
0
12
0
0
0
0
12
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _