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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS3 All Species: 23.94
Human Site: S668 Identified Species: 47.88
UniProt: Q68E01 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68E01 NP_075391.3 1043 118070 S668 C Q M Q E D N S S F S L L L D
Chimpanzee Pan troglodytes XP_001143923 1108 125002 S667 C Q M Q E D N S S F S L L L D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852591 1046 117423 S670 C Q M Q E D N S S F S L L L D
Cat Felis silvestris
Mouse Mus musculus Q7TPD0 1041 117919 S666 C Q M Q E D N S S F S L L L D
Rat Rattus norvegicus XP_342289 1041 117877 S666 C Q M Q E D N S S F S L L L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235108 302 34498
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXC9 1017 116384 S644 C Q M Q E D N S G F S V L L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7PLS8 1068 123932 K674 F L Y E N D E K S K K P F Q T
Honey Bee Apis mellifera XP_394651 1035 118020 D635 F Q L C K E E D N R R K L L A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786914 388 44969 V32 M E R G H D V V S K A T A G L
Poplar Tree Populus trichocarpa XP_002298478 995 112510 H621 P S S D S G I H S P T I L I A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193195 508 59017 S152 W E C L L D D S P L V L T S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 N.A. 93.9 N.A. 98.5 98.3 N.A. N.A. 25.5 N.A. 83.3 N.A. 39 46 N.A. 24.2
Protein Similarity: 100 94 N.A. 95 N.A. 99.3 99.2 N.A. N.A. 27.5 N.A. 91 N.A. 60 66.9 N.A. 29.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 N.A. 86.6 N.A. 13.3 20 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 N.A. 93.3 N.A. 20 46.6 N.A. 26.6
Percent
Protein Identity: 24.6 N.A. N.A. 20.7 N.A. N.A.
Protein Similarity: 43.6 N.A. N.A. 33.4 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 25 % A
% Cys: 50 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 75 9 9 0 0 0 0 0 0 50 % D
% Glu: 0 17 0 9 50 9 17 0 0 0 0 0 0 0 0 % E
% Phe: 17 0 0 0 0 0 0 0 0 50 0 0 9 0 0 % F
% Gly: 0 0 0 9 0 9 0 0 9 0 0 0 0 9 0 % G
% His: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 9 0 9 0 % I
% Lys: 0 0 0 0 9 0 0 9 0 17 9 9 0 0 0 % K
% Leu: 0 9 9 9 9 0 0 0 0 9 0 50 67 59 9 % L
% Met: 9 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 50 0 9 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 9 9 0 9 0 0 0 % P
% Gln: 0 59 0 50 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 9 9 0 0 0 0 % R
% Ser: 0 9 9 0 9 0 0 59 67 0 50 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 9 % T
% Val: 0 0 0 0 0 0 9 9 0 0 9 9 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _