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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS3 All Species: 27.58
Human Site: S854 Identified Species: 55.15
UniProt: Q68E01 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68E01 NP_075391.3 1043 118070 S854 Q L R R E K P S E E M V K M V
Chimpanzee Pan troglodytes XP_001143923 1108 125002 S853 Q L R R E K P S E E M V K M V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852591 1046 117423 S856 Q L R R E N S S P G M W A S S
Cat Felis silvestris
Mouse Mus musculus Q7TPD0 1041 117919 S852 Q L R R E K P S E E M V K M V
Rat Rattus norvegicus XP_342289 1041 117877 S852 Q L R R E K P S E E M V K M V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235108 302 34498 K119 W L F F N P E K D S I M N I E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXC9 1017 116384 S830 Q L R R E K P S E E M V K M V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7PLS8 1068 123932 T869 L L K N E E P T N E I I R L M
Honey Bee Apis mellifera XP_394651 1035 118020 T821 M L K Q E K P T L E L L R Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786914 388 44969 V205 T H L R D R E V E F C V Q L I
Poplar Tree Populus trichocarpa XP_002298478 995 112510 R798 A G N I D I I R F L V S Q L D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193195 508 59017 E325 A I I G W L L E L C R Q N H H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 N.A. 93.9 N.A. 98.5 98.3 N.A. N.A. 25.5 N.A. 83.3 N.A. 39 46 N.A. 24.2
Protein Similarity: 100 94 N.A. 95 N.A. 99.3 99.2 N.A. N.A. 27.5 N.A. 91 N.A. 60 66.9 N.A. 29.3
P-Site Identity: 100 100 N.A. 46.6 N.A. 100 100 N.A. N.A. 6.6 N.A. 100 N.A. 26.6 33.3 N.A. 20
P-Site Similarity: 100 100 N.A. 46.6 N.A. 100 100 N.A. N.A. 33.3 N.A. 100 N.A. 80 80 N.A. 53.3
Percent
Protein Identity: 24.6 N.A. N.A. 20.7 N.A. N.A.
Protein Similarity: 43.6 N.A. N.A. 33.4 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 0 0 9 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 67 9 17 9 50 59 0 0 0 0 9 % E
% Phe: 0 0 9 9 0 0 0 0 9 9 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 9 % H
% Ile: 0 9 9 9 0 9 9 0 0 0 17 9 0 9 9 % I
% Lys: 0 0 17 0 0 50 0 9 0 0 0 0 42 0 0 % K
% Leu: 9 75 9 0 0 9 9 0 17 9 9 9 0 25 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 50 9 0 42 9 % M
% Asn: 0 0 9 9 9 9 0 0 9 0 0 0 17 0 0 % N
% Pro: 0 0 0 0 0 9 59 0 9 0 0 0 0 0 0 % P
% Gln: 50 0 0 9 0 0 0 0 0 0 0 9 17 9 0 % Q
% Arg: 0 0 50 59 0 9 0 9 0 0 9 0 17 0 0 % R
% Ser: 0 0 0 0 0 0 9 50 0 9 0 9 0 9 9 % S
% Thr: 9 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 9 50 0 0 42 % V
% Trp: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _