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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP17
All Species:
18.48
Human Site:
S474
Identified Species:
40.67
UniProt:
Q68EM7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68EM7
NP_001006635.1
881
95437
S474
H
T
G
N
D
S
D
S
G
T
L
E
R
K
R
Chimpanzee
Pan troglodytes
XP_510887
881
95444
S474
H
T
G
N
D
S
D
S
G
T
L
E
R
K
R
Rhesus Macaque
Macaca mulatta
XP_001090267
877
94245
S470
H
T
G
N
D
S
D
S
G
T
L
E
R
K
R
Dog
Lupus familis
XP_547084
898
96108
S479
H
T
G
N
D
S
D
S
G
T
L
E
R
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UIA2
846
92184
E452
E
V
E
F
N
V
S
E
A
F
V
P
L
A
T
Rat
Rattus norvegicus
Q99N37
858
93735
S462
V
P
L
A
T
P
N
S
N
H
S
S
H
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521066
476
51957
P82
K
P
P
A
P
V
L
P
L
E
G
A
A
P
P
Chicken
Gallus gallus
XP_414864
881
95496
S475
H
T
G
N
E
Y
D
S
G
T
L
E
R
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108378
535
59728
L142
I
Q
K
Q
R
R
H
L
A
K
L
V
L
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDS5
740
83067
R347
N
L
Y
K
D
F
I
R
I
A
E
R
H
S
E
Honey Bee
Apis mellifera
XP_395006
799
89540
W406
V
I
A
P
N
L
I
W
S
P
Q
E
D
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.1
87.5
N.A.
84.9
83
N.A.
27
72.5
N.A.
42.6
N.A.
25.7
31.6
N.A.
N.A.
Protein Similarity:
100
99.8
93.1
90.6
N.A.
88.1
86.2
N.A.
34.5
82.9
N.A.
51.1
N.A.
44.3
48
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
6.6
N.A.
0
86.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
0
93.3
N.A.
6.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
0
0
0
0
19
10
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
46
0
46
0
0
0
0
0
10
10
0
% D
% Glu:
10
0
10
0
10
0
0
10
0
10
10
55
0
0
10
% E
% Phe:
0
0
0
10
0
10
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
46
0
0
0
0
0
46
0
10
0
0
0
10
% G
% His:
46
0
0
0
0
0
10
0
0
10
0
0
19
0
0
% H
% Ile:
10
10
0
0
0
0
19
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
10
10
0
0
0
0
0
10
0
0
0
46
0
% K
% Leu:
0
10
10
0
0
10
10
10
10
0
55
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
46
19
0
10
0
10
0
0
0
0
0
10
% N
% Pro:
0
19
10
10
10
10
0
10
0
10
0
10
0
10
10
% P
% Gln:
0
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
0
10
0
0
0
10
46
0
46
% R
% Ser:
0
0
0
0
0
37
10
55
10
0
10
10
0
10
0
% S
% Thr:
0
46
0
0
10
0
0
0
0
46
0
0
0
10
10
% T
% Val:
19
10
0
0
0
19
0
0
0
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _