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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHM1P All Species: 17.27
Human Site: T263 Identified Species: 38
UniProt: Q69YJ1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YJ1 XP_002347841 520 58973 T263 E T A E E A V T L G G S L D E
Chimpanzee Pan troglodytes XP_001140498 1061 118011 T793 E T A E E A V T L G G S L D E
Rhesus Macaque Macaca mulatta XP_001099880 587 66762 Q336 R S S E Q N L Q V T L R N K P
Dog Lupus familis XP_548048 1056 117749 T788 E I A E E A V T L G G S L D E
Cat Felis silvestris
Mouse Mus musculus Q7TSI1 1074 118516 T806 E S A E E A V T L G G S L D E
Rat Rattus norvegicus Q5PQS0 1059 117490 T791 E S V Q E A V T L A G S L D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q08AW4 748 85595 K458 S L L V P L R K K S K E N Q S
Zebra Danio Brachydanio rerio NP_001082872 845 95085 A577 D D G A G A S A A D G A Q G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTT9 492 55389 A236 I C P E I G L A S Q G Y K C A
Honey Bee Apis mellifera XP_395844 660 73853 D284 I E I N M C N D I E D S A I E
Nematode Worm Caenorhab. elegans O01738 486 56489 C229 F E L N T N L C E E R S L A E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.6 29.1 44.4 N.A. 43.2 43.4 N.A. N.A. N.A. 24.6 28.6 N.A. 23.6 24.7 22.3 N.A.
Protein Similarity: 100 48.1 47.5 46.2 N.A. 45.2 45.8 N.A. N.A. N.A. 39.7 41.1 N.A. 43.4 42.2 38.8 N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 73.3 N.A. N.A. N.A. 0 13.3 N.A. 13.3 13.3 20 N.A.
P-Site Similarity: 100 100 40 93.3 N.A. 100 86.6 N.A. N.A. N.A. 0 26.6 N.A. 20 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 37 10 0 55 0 19 10 10 0 10 10 10 10 % A
% Cys: 0 10 0 0 0 10 0 10 0 0 0 0 0 10 0 % C
% Asp: 10 10 0 0 0 0 0 10 0 10 10 0 0 46 0 % D
% Glu: 46 19 0 55 46 0 0 0 10 19 0 10 0 0 64 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 10 10 0 0 0 37 64 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 10 10 0 10 0 0 0 10 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 10 10 0 10 0 10 10 0 % K
% Leu: 0 10 19 0 0 10 28 0 46 0 10 0 55 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 19 0 19 10 0 0 0 0 0 19 0 0 % N
% Pro: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 10 10 0 0 10 0 10 0 0 10 10 0 % Q
% Arg: 10 0 0 0 0 0 10 0 0 0 10 10 0 0 0 % R
% Ser: 10 28 10 0 0 0 10 0 10 10 0 64 0 0 10 % S
% Thr: 0 19 0 0 10 0 0 46 0 10 0 0 0 0 0 % T
% Val: 0 0 10 10 0 0 46 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _