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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L1
All Species:
24.55
Human Site:
S127
Identified Species:
36
UniProt:
Q69YN2
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q69YN2
NP_060764.3
538
60619
S127
N
E
P
V
P
G
Y
S
F
S
P
K
D
V
S
Chimpanzee
Pan troglodytes
XP_507980
538
60617
S127
N
E
P
V
P
G
Y
S
F
S
P
K
D
V
S
Rhesus Macaque
Macaca mulatta
XP_001099292
573
64594
N163
N
E
P
V
P
G
Y
N
F
S
P
K
D
V
S
Dog
Lupus familis
XP_534991
537
60735
S127
N
E
P
V
P
G
Y
S
F
S
P
K
D
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI33
537
60233
S127
D
E
P
V
P
A
H
S
F
S
P
K
D
V
S
Rat
Rattus norvegicus
NP_001102398
537
60359
S127
D
E
P
V
P
A
Y
S
F
S
P
K
D
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513071
656
71829
S247
A
E
P
G
P
S
Y
S
F
S
A
K
D
V
T
Chicken
Gallus gallus
XP_001234092
536
59948
S127
D
E
P
T
P
A
Y
S
F
S
S
K
D
V
T
Frog
Xenopus laevis
Q8AVL0
540
60824
C129
S
E
P
A
P
A
Y
C
F
T
A
K
D
V
T
Zebra Danio
Brachydanio rerio
Q5RGJ5
544
61426
C129
Q
E
P
A
P
S
H
C
F
T
P
K
D
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z8J0
545
62135
G147
Q
G
T
A
D
S
A
G
S
E
H
E
F
T
K
Honey Bee
Apis mellifera
XP_396187
523
59880
C125
S
S
E
T
K
S
I
C
F
D
E
N
D
V
M
Nematode Worm
Caenorhab. elegans
O16216
533
58943
L121
V
E
G
S
S
K
D
L
S
C
F
D
K
A
D
Sea Urchin
Strong. purpuratus
XP_783052
530
60015
W123
D
V
L
L
T
S
Q
W
P
A
N
V
T
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WU9
596
66403
G124
L
S
V
A
Y
L
S
G
R
Q
S
S
E
S
Q
Baker's Yeast
Sacchar. cerevisiae
P53255
507
58188
I111
L
Q
G
E
K
K
S
I
L
D
E
F
G
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
90.7
94.2
N.A.
89.4
89.7
N.A.
64.9
71
69.6
65.8
N.A.
38.9
45.9
42.5
46.2
Protein Similarity:
100
99.2
92.1
97.5
N.A.
94.8
94.8
N.A.
73.1
81
82.7
81
N.A.
56.8
66.7
58.9
64.8
P-Site Identity:
100
100
93.3
100
N.A.
80
86.6
N.A.
66.6
66.6
53.3
46.6
N.A.
0
20
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
80
73.3
73.3
N.A.
6.6
26.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
47.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
25
0
25
7
0
0
7
13
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
19
0
7
0
0
0
0
0
% C
% Asp:
25
0
0
0
7
0
7
0
0
13
0
7
69
0
7
% D
% Glu:
0
69
7
7
0
0
0
0
0
7
13
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
69
0
7
7
7
0
7
% F
% Gly:
0
7
13
7
0
25
0
13
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
7
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
13
13
0
0
0
0
0
63
7
7
7
% K
% Leu:
13
0
7
7
0
7
0
7
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
25
0
0
0
0
0
0
7
0
0
7
7
0
0
0
% N
% Pro:
0
0
63
0
63
0
0
0
7
0
44
0
0
0
0
% P
% Gln:
13
7
0
0
0
0
7
0
0
7
0
0
0
7
7
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
13
13
0
7
7
32
13
44
13
50
13
7
0
7
44
% S
% Thr:
0
0
7
13
7
0
0
0
0
13
0
0
7
7
25
% T
% Val:
7
7
7
38
0
0
0
0
0
0
0
7
0
63
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _