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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L1 All Species: 21.82
Human Site: S303 Identified Species: 32
UniProt: Q69YN2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YN2 NP_060764.3 538 60619 S303 E K Q G R K R S S T G R D S K
Chimpanzee Pan troglodytes XP_507980 538 60617 S303 E K Q G R K R S S T G R D S K
Rhesus Macaque Macaca mulatta XP_001099292 573 64594 S339 E K Q G R K R S S T G R D S K
Dog Lupus familis XP_534991 537 60735 S303 E K Q G R K R S S T G R D N K
Cat Felis silvestris
Mouse Mus musculus Q8CI33 537 60233 P303 E K Q G R K R P S T G R D T R
Rat Rattus norvegicus NP_001102398 537 60359 S303 E K Q G R K R S S T G R D N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513071 656 71829 P423 K Q Q G K K R P S S G E G N H
Chicken Gallus gallus XP_001234092 536 59948 P303 K H Q G K K R P S D G K D R G
Frog Xenopus laevis Q8AVL0 540 60824 Q306 K P Q G K K R Q T D G K G G R
Zebra Danio Brachydanio rerio Q5RGJ5 544 61426 Q312 R Q H G R K R Q S D G D R P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z8J0 545 62135 R317 M D G G R R K R Q G G D N N K
Honey Bee Apis mellifera XP_396187 523 59880 S298 S K E T S K R S K S S E G S N
Nematode Worm Caenorhab. elegans O16216 533 58943 G301 A E D G A G N G R K R H N D G
Sea Urchin Strong. purpuratus XP_783052 530 60015 Q303 R Q H D G Q G Q H D G Q R Q H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU9 596 66403 S357 C E K G P E C S Y K H E F Q D
Baker's Yeast Sacchar. cerevisiae P53255 507 58188 I284 N L E D H M I I S I G K L V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.7 94.2 N.A. 89.4 89.7 N.A. 64.9 71 69.6 65.8 N.A. 38.9 45.9 42.5 46.2
Protein Similarity: 100 99.2 92.1 97.5 N.A. 94.8 94.8 N.A. 73.1 81 82.7 81 N.A. 56.8 66.7 58.9 64.8
P-Site Identity: 100 100 100 93.3 N.A. 80 93.3 N.A. 40 46.6 33.3 40 N.A. 26.6 33.3 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 73.3 66.6 66.6 46.6 N.A. 53.3 46.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33.7 28 N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 13 0 0 0 0 0 25 0 13 44 7 7 % D
% Glu: 38 13 13 0 0 7 0 0 0 0 0 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 7 82 7 7 7 7 0 7 82 0 19 7 13 % G
% His: 0 7 13 0 7 0 0 0 7 0 7 7 0 0 13 % H
% Ile: 0 0 0 0 0 0 7 7 0 7 0 0 0 0 0 % I
% Lys: 19 44 7 0 19 69 7 0 7 13 0 19 0 0 38 % K
% Leu: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % L
% Met: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 0 13 25 13 % N
% Pro: 0 7 0 0 7 0 0 19 0 0 0 0 0 7 0 % P
% Gln: 0 19 57 0 0 7 0 19 7 0 0 7 0 13 0 % Q
% Arg: 13 0 0 0 50 7 69 7 7 0 7 38 13 7 13 % R
% Ser: 7 0 0 0 7 0 0 44 63 13 7 0 0 25 0 % S
% Thr: 0 0 0 7 0 0 0 0 7 38 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _