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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L1 All Species: 35.76
Human Site: S304 Identified Species: 52.44
UniProt: Q69YN2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YN2 NP_060764.3 538 60619 S304 K Q G R K R S S T G R D S K S
Chimpanzee Pan troglodytes XP_507980 538 60617 S304 K Q G R K R S S T G R D S K S
Rhesus Macaque Macaca mulatta XP_001099292 573 64594 S340 K Q G R K R S S T G R D S K S
Dog Lupus familis XP_534991 537 60735 S304 K Q G R K R S S T G R D N K S
Cat Felis silvestris
Mouse Mus musculus Q8CI33 537 60233 S304 K Q G R K R P S T G R D T R P
Rat Rattus norvegicus NP_001102398 537 60359 S304 K Q G R K R S S T G R D N K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513071 656 71829 S424 Q Q G K K R P S S G E G N H S
Chicken Gallus gallus XP_001234092 536 59948 S304 H Q G K K R P S D G K D R G S
Frog Xenopus laevis Q8AVL0 540 60824 T307 P Q G K K R Q T D G K G G R Q
Zebra Danio Brachydanio rerio Q5RGJ5 544 61426 S313 Q H G R K R Q S D G D R P N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z8J0 545 62135 Q318 D G G R R K R Q G G D N N K R
Honey Bee Apis mellifera XP_396187 523 59880 K299 K E T S K R S K S S E G S N K
Nematode Worm Caenorhab. elegans O16216 533 58943 R302 E D G A G N G R K R H N D G G
Sea Urchin Strong. purpuratus XP_783052 530 60015 H304 Q H D G Q G Q H D G Q R Q H K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU9 596 66403 Y358 E K G P E C S Y K H E F Q D E
Baker's Yeast Sacchar. cerevisiae P53255 507 58188 S285 L E D H M I I S I G K L V Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.7 94.2 N.A. 89.4 89.7 N.A. 64.9 71 69.6 65.8 N.A. 38.9 45.9 42.5 46.2
Protein Similarity: 100 99.2 92.1 97.5 N.A. 94.8 94.8 N.A. 73.1 81 82.7 81 N.A. 56.8 66.7 58.9 64.8
P-Site Identity: 100 100 100 93.3 N.A. 73.3 86.6 N.A. 46.6 53.3 33.3 40 N.A. 26.6 33.3 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 73.3 66.6 60 46.6 N.A. 53.3 46.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33.7 28 N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 13 0 0 0 0 0 25 0 13 44 7 7 0 % D
% Glu: 13 13 0 0 7 0 0 0 0 0 19 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 7 82 7 7 7 7 0 7 82 0 19 7 13 7 % G
% His: 7 13 0 7 0 0 0 7 0 7 7 0 0 13 0 % H
% Ile: 0 0 0 0 0 7 7 0 7 0 0 0 0 0 0 % I
% Lys: 44 7 0 19 69 7 0 7 13 0 19 0 0 38 13 % K
% Leu: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 13 25 13 0 % N
% Pro: 7 0 0 7 0 0 19 0 0 0 0 0 7 0 13 % P
% Gln: 19 57 0 0 7 0 19 7 0 0 7 0 13 0 13 % Q
% Arg: 0 0 0 50 7 69 7 7 0 7 38 13 7 13 7 % R
% Ser: 0 0 0 7 0 0 44 63 13 7 0 0 25 0 38 % S
% Thr: 0 0 7 0 0 0 0 7 38 0 0 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _