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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L1 All Species: 12.42
Human Site: S309 Identified Species: 18.22
UniProt: Q69YN2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YN2 NP_060764.3 538 60619 S309 R S S T G R D S K S S P H P K
Chimpanzee Pan troglodytes XP_507980 538 60617 S309 R S S T G R D S K S S P H P K
Rhesus Macaque Macaca mulatta XP_001099292 573 64594 S345 R S S T G R D S K S P H P K Q
Dog Lupus familis XP_534991 537 60735 N309 R S S T G R D N K S P H P K Q
Cat Felis silvestris
Mouse Mus musculus Q8CI33 537 60233 T309 R P S T G R D T R P P H A K Q
Rat Rattus norvegicus NP_001102398 537 60359 N309 R S S T G R D N K P P H A K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513071 656 71829 N429 R P S S G E G N H S R P K Q L
Chicken Gallus gallus XP_001234092 536 59948 R309 R P S D G K D R G S S Q T K Q
Frog Xenopus laevis Q8AVL0 540 60824 G312 R Q T D G K G G R Q S Q A K Q
Zebra Danio Brachydanio rerio Q5RGJ5 544 61426 P318 R Q S D G D R P N Q H K Q P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z8J0 545 62135 N323 K R Q G G D N N K R D K R P R
Honey Bee Apis mellifera XP_396187 523 59880 S304 R S K S S E G S N K R S K P E
Nematode Worm Caenorhab. elegans O16216 533 58943 D307 N G R K R H N D G G N D G P R
Sea Urchin Strong. purpuratus XP_783052 530 60015 Q309 G Q H D G Q R Q H K M P M K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU9 596 66403 Q363 C S Y K H E F Q D E S S I Q R
Baker's Yeast Sacchar. cerevisiae P53255 507 58188 V290 I I S I G K L V Y L T T A K G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.7 94.2 N.A. 89.4 89.7 N.A. 64.9 71 69.6 65.8 N.A. 38.9 45.9 42.5 46.2
Protein Similarity: 100 99.2 92.1 97.5 N.A. 94.8 94.8 N.A. 73.1 81 82.7 81 N.A. 56.8 66.7 58.9 64.8
P-Site Identity: 100 100 66.6 60 N.A. 40 53.3 N.A. 33.3 40 20 26.6 N.A. 20 26.6 6.6 13.3
P-Site Similarity: 100 100 73.3 73.3 N.A. 60 60 N.A. 46.6 53.3 46.6 33.3 N.A. 46.6 40 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 33.7 28 N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 25 0 13 44 7 7 0 7 7 0 0 0 % D
% Glu: 0 0 0 0 0 19 0 0 0 7 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 7 7 0 7 82 0 19 7 13 7 0 0 7 0 7 % G
% His: 0 0 7 0 7 7 0 0 13 0 7 25 13 0 7 % H
% Ile: 7 7 0 7 0 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 7 0 7 13 0 19 0 0 38 13 0 13 13 50 13 % K
% Leu: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % M
% Asn: 7 0 0 0 0 0 13 25 13 0 7 0 0 0 0 % N
% Pro: 0 19 0 0 0 0 0 7 0 13 25 25 13 38 0 % P
% Gln: 0 19 7 0 0 7 0 13 0 13 0 13 7 13 32 % Q
% Arg: 69 7 7 0 7 38 13 7 13 7 13 0 7 0 25 % R
% Ser: 0 44 63 13 7 0 0 25 0 38 32 13 0 0 7 % S
% Thr: 0 0 7 38 0 0 0 7 0 0 7 7 7 0 0 % T
% Val: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _