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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L1 All Species: 9.09
Human Site: T520 Identified Species: 13.33
UniProt: Q69YN2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YN2 NP_060764.3 538 60619 T520 I S K E D E E T L A R R F R K
Chimpanzee Pan troglodytes XP_507980 538 60617 T520 I S K E D E E T L A R R F R K
Rhesus Macaque Macaca mulatta XP_001099292 573 64594 T555 I S K E D E E T L A R R F Q K
Dog Lupus familis XP_534991 537 60735 M519 L S K E E E E M L A R R F R K
Cat Felis silvestris
Mouse Mus musculus Q8CI33 537 60233 A519 T S K D E E E A L A R R F R K
Rat Rattus norvegicus NP_001102398 537 60359 A519 T S K D E E E A L A R R F R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513071 656 71829 A638 L G R E E E V A Q S R L F R G
Chicken Gallus gallus XP_001234092 536 59948 A518 A A R P E E A A Q A S A F R R
Frog Xenopus laevis Q8AVL0 540 60824 D522 S S R A E E E D L T K T F R D
Zebra Danio Brachydanio rerio Q5RGJ5 544 61426 D526 I S R E E E E D Q A K Q V R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z8J0 545 62135 A528 L D K D E E V A Y V E D F R K
Honey Bee Apis mellifera XP_396187 523 59880 E504 D C Q M D E E E E I E L A K R
Nematode Worm Caenorhab. elegans O16216 533 58943 E512 L A K E K E V E L V N K L K S
Sea Urchin Strong. purpuratus XP_783052 530 60015 G513 S T S K E E E G Q L V S T F R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU9 596 66403 E576 R N C K I S Q E E E A K L A E
Baker's Yeast Sacchar. cerevisiae P53255 507 58188 I488 Q T K Q Q E T I E A E K F Q K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.7 94.2 N.A. 89.4 89.7 N.A. 64.9 71 69.6 65.8 N.A. 38.9 45.9 42.5 46.2
Protein Similarity: 100 99.2 92.1 97.5 N.A. 94.8 94.8 N.A. 73.1 81 82.7 81 N.A. 56.8 66.7 58.9 64.8
P-Site Identity: 100 100 93.3 80 N.A. 73.3 73.3 N.A. 33.3 26.6 40 46.6 N.A. 33.3 20 26.6 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 60 53.3 60 73.3 N.A. 53.3 40 53.3 40
Percent
Protein Identity: N.A. N.A. N.A. 33.7 28 N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 0 7 0 0 7 32 0 57 7 7 7 7 0 % A
% Cys: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 19 25 0 0 13 0 0 0 7 0 0 7 % D
% Glu: 0 0 0 44 57 94 63 19 19 7 19 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 69 7 0 % F
% Gly: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 25 0 0 0 7 0 0 7 0 7 0 0 0 0 0 % I
% Lys: 0 0 57 13 7 0 0 0 0 0 13 19 0 13 50 % K
% Leu: 25 0 0 0 0 0 0 0 50 7 0 13 13 0 0 % L
% Met: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 7 7 7 0 7 0 25 0 0 7 0 13 0 % Q
% Arg: 7 0 25 0 0 0 0 0 0 0 44 38 0 63 19 % R
% Ser: 13 50 7 0 0 7 0 0 0 7 7 7 0 0 13 % S
% Thr: 13 13 0 0 0 0 7 19 0 7 0 7 7 0 0 % T
% Val: 0 0 0 0 0 0 19 0 0 13 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _