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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L1 All Species: 35.15
Human Site: T58 Identified Species: 51.56
UniProt: Q69YN2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YN2 NP_060764.3 538 60619 T58 A E W E E Y K T G I K K A P I
Chimpanzee Pan troglodytes XP_507980 538 60617 T58 A E W E E Y K T G I K K A P I
Rhesus Macaque Macaca mulatta XP_001099292 573 64594 T94 A E W E E Y K T G I K K A P I
Dog Lupus familis XP_534991 537 60735 T58 A E W E K Y K T G I K K A P I
Cat Felis silvestris
Mouse Mus musculus Q8CI33 537 60233 T58 A E W E E Y K T G N K K A P I
Rat Rattus norvegicus NP_001102398 537 60359 T58 A A W E E Y R T G S K K A P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513071 656 71829 K178 A E W E A Y R K G V K K A P I
Chicken Gallus gallus XP_001234092 536 59948 S58 A E W A E Y R S G A K K A P I
Frog Xenopus laevis Q8AVL0 540 60824 S60 T H W D E Y K S G A K K A P I
Zebra Danio Brachydanio rerio Q5RGJ5 544 61426 S60 A E W A T Y K S G A K K A P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z8J0 545 62135 K78 N E E L I A Y K N G F K H I T
Honey Bee Apis mellifera XP_396187 523 59880 I56 T E L D D Y K I G I K N I P V
Nematode Worm Caenorhab. elegans O16216 533 58943 N52 F G D D D D S N E K V I N G N
Sea Urchin Strong. purpuratus XP_783052 530 60015 D54 F D N K E G G D V C E N L T Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU9 596 66403 Y55 I L D E F L D Y V E G R A Q V
Baker's Yeast Sacchar. cerevisiae P53255 507 58188 S42 L I I I F S N S Y D E N F E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.7 94.2 N.A. 89.4 89.7 N.A. 64.9 71 69.6 65.8 N.A. 38.9 45.9 42.5 46.2
Protein Similarity: 100 99.2 92.1 97.5 N.A. 94.8 94.8 N.A. 73.1 81 82.7 81 N.A. 56.8 66.7 58.9 64.8
P-Site Identity: 100 100 100 93.3 N.A. 93.3 80 N.A. 73.3 73.3 66.6 73.3 N.A. 13.3 46.6 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 86.6 86.6 80 80 N.A. 13.3 66.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33.7 28 N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 57 7 0 13 7 7 0 0 0 19 0 0 69 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 7 13 19 13 7 7 7 0 7 0 0 0 0 0 % D
% Glu: 0 63 7 50 50 0 0 0 7 7 13 0 0 7 0 % E
% Phe: 13 0 0 0 13 0 0 0 0 0 7 0 7 0 0 % F
% Gly: 0 7 0 0 0 7 7 0 69 7 7 0 0 7 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 7 7 7 7 7 0 0 7 0 32 0 7 7 7 63 % I
% Lys: 0 0 0 7 7 0 50 13 0 7 69 69 0 0 0 % K
% Leu: 7 7 7 7 0 7 0 0 0 0 0 0 7 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 0 0 0 7 7 7 7 0 19 7 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 69 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 19 0 0 0 0 7 0 0 0 % R
% Ser: 0 0 0 0 0 7 7 25 0 7 0 0 0 0 0 % S
% Thr: 13 0 0 0 7 0 0 38 0 0 0 0 0 7 7 % T
% Val: 0 0 0 0 0 0 0 0 13 7 7 0 0 0 13 % V
% Trp: 0 0 63 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 69 7 7 7 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _