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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L1 All Species: 51.21
Human Site: Y239 Identified Species: 75.11
UniProt: Q69YN2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q69YN2 NP_060764.3 538 60619 Y239 P E K K K Y L Y A F S I V P M
Chimpanzee Pan troglodytes XP_507980 538 60617 Y239 P E K K K Y L Y A F S I V P M
Rhesus Macaque Macaca mulatta XP_001099292 573 64594 Y275 P E K K K Y L Y A F S I V P M
Dog Lupus familis XP_534991 537 60735 Y239 P E K K K Y L Y A F S I V P M
Cat Felis silvestris
Mouse Mus musculus Q8CI33 537 60233 Y239 P E K K K Y L Y A F S I V P M
Rat Rattus norvegicus NP_001102398 537 60359 Y239 P E K K K Y L Y A F S I V P M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513071 656 71829 Y359 P D K K K Y L Y A F N L L P M
Chicken Gallus gallus XP_001234092 536 59948 Y239 T S K K K Y L Y A F S I V P M
Frog Xenopus laevis Q8AVL0 540 60824 Y241 L D K K K Y I Y A F N I V P M
Zebra Danio Brachydanio rerio Q5RGJ5 544 61426 Y240 P A K K K Y L Y A F N I I P M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z8J0 545 62135 Y259 A E K A K Y I Y A L S L K P V
Honey Bee Apis mellifera XP_396187 523 59880 Y236 N Q K K K W L Y A L N L T P V
Nematode Worm Caenorhab. elegans O16216 533 58943 Y232 P E K Q K W L Y A C N V K P M
Sea Urchin Strong. purpuratus XP_783052 530 60015 E241 S K R E E P K E T D Q F F F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU9 596 66403 H241 K N K Q K F L H A L S P T P T
Baker's Yeast Sacchar. cerevisiae P53255 507 58188 S225 L I A N P Y N S V V T N S N K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.7 94.2 N.A. 89.4 89.7 N.A. 64.9 71 69.6 65.8 N.A. 38.9 45.9 42.5 46.2
Protein Similarity: 100 99.2 92.1 97.5 N.A. 94.8 94.8 N.A. 73.1 81 82.7 81 N.A. 56.8 66.7 58.9 64.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 86.6 73.3 80 N.A. 53.3 46.6 60 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 93.3 93.3 N.A. 73.3 80 86.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33.7 28 N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 40 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 0 0 0 88 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 50 0 7 7 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 63 0 7 7 7 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 13 0 0 0 0 57 7 0 0 % I
% Lys: 7 7 88 69 88 0 7 0 0 0 0 0 13 0 7 % K
% Leu: 13 0 0 0 0 0 75 0 0 19 0 19 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69 % M
% Asn: 7 7 0 7 0 0 7 0 0 0 32 7 0 7 0 % N
% Pro: 57 0 0 0 7 7 0 0 0 0 0 7 0 88 0 % P
% Gln: 0 7 0 13 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 0 0 0 0 0 7 0 0 57 0 7 0 7 % S
% Thr: 7 0 0 0 0 0 0 0 7 0 7 0 13 0 7 % T
% Val: 0 0 0 0 0 0 0 0 7 7 0 7 50 0 13 % V
% Trp: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 75 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _